Evidence map›Paper›PMID 23732853›Full record

ReviewCold Spring Harbor perspectives in medicine2013

Management of the thalassemias.

Nancy F Olivieri, Gary M Brittenham

Abstract readReview
In one paragraph

Review in Cold Spring Harbor perspectives in medicine, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Challenges in chronic transfusion for patients with thalassemia.Hematology. American Society of Hematology. Education Program · 2020
    Review
  5. Thalassemia: Common Clinical Queries in Management.Indian journal of pediatrics · 2020
    Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Current understanding of iron homeostasis.The American journal of clinical nutrition · 2017
    Review
  11. The Regulation of Iron Absorption and Homeostasis.The Clinical biochemist. Reviews · 2016
    Review
  12. Review
  13. The hemoglobin E thalassemias.Cold Spring Harbor perspectives in medicine · 2012
    Review
  14. β-thalassemia intermedia: a clinical perspective.Cold Spring Harbor perspectives in medicine · 2012
    Review
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Nancy F OlivieriHemoglobinopathy Research University Health Network, Toronto, Ontario M5G 2C4, Canada.
Gary M Brittenham

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

During the last 30 years, in addition to the considerable progress made in control and prevention of thalassemias(3), there have also been major advances in their symptomatic management, at least in wealthier countries where appropriate facilities are available. Remarkable improvements in survival in the severe forms of thalassemia have followed the more judicious use of blood transfusion and, in particular, the ability to manage the iron accumulation resulting from transfusion with its severe and ultimately lethal effects on endocrine and cardiac function.

Indexed as

BenzoatesBlood TransfusionDeferasiroxDeferiproneDeferoxamineFerritinsHumansIronIron Chelating AgentsIron OverloadLiverMyocardiumPancreasPituitary Gland, AnteriorPyridonesThalassemiaBenzoatesDeferasiroxDeferiproneDeferoxamineFerritinsIronIron Chelating AgentsPyridonesTriazoles

Identifiers

PMID23732853
PMCPMC3662352

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.