Trial reportThe journal of nutrition, health & aging2013
A Jerte valley cherry product provides beneficial effects on sleep quality. Influence on aging.
Trial report in The journal of nutrition, health & aging, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
25 citing papers in PubMed, 2 syntheses or guidelines pooled it, 55 citations in OpenAlex.
- Dietary Supplement Interventions and Sleep Quality Improvement: A Systematic Review and Meta-Analysis.Nutrients · 2025Pooled it
- Pooled it
- Commonly Used Dose of Montmorency Tart Cherry Powder Does Not Improve Sleep or Inflammation Outcomes in Individuals with Overweight or Obesity.Nutrients · 2024Trial
- Effectiveness of Melatonin-Containing Foods on Promoting Sleep: A Scoping Review.Food science & nutrition · 2026Review
- Association of alternative healthy eating index with sleep quality among female students.BMC research notes · 2025Article
- Current Aspects of Selected Factors to Modulate Brain Health and Sports Performance in Athletes.Nutrients · 2024Review
- A View on the Chemical and Biological Attributes of Five Edible Fruits after Finishing Their Shelf Life: Studies on Caco-2 Cells.International journal of molecular sciences · 2024Article
- Berry Consumption and Sleep in the Adult US General Population: Results from the National Health and Nutrition Examination Survey 2005-2018.Nutrients · 2023Article
- Diversity of Culture Microorganisms from Portuguese Sweet Cherries.Life (Basel, Switzerland) · 2023Article
- The Complex Effects of Light on Metabolism in Humans.Nutrients · 2023Review
- Acute effects of fresh versus dried Hayward green kiwifruit on sleep quality, mood, and sleep-related urinary metabolites in healthy young men with good and poor sleep quality.Frontiers in nutrition · 2023Article
- Association between low carbohydrate diet (LCD) and sleep quality by mediating role of inflammatory factors in women with overweight and obesity: A cross-sectional study.Food science & nutrition · 2021Article
- Association of dietary total antioxidant capacity with depression, anxiety, and sleep disorders: A systematic review of observational studies.Journal of clinical and translational research · 2021Review
- Sleep and Diet: Mounting Evidence of a Cyclical Relationship.Annual review of nutrition · 2021Article
- Thirty Days of Montmorency Tart Cherry Supplementation Has No Effect on Gut Microbiome Composition, Inflammation, or Glycemic Control in Healthy Adults.Frontiers in nutrition · 2021Article
- Effects of Diet on Sleep: A Narrative Review.Nutrients · 2020Review
- Self-reported sleep disturbance in Crohn's disease is not confirmed by objective sleep measures.Scientific reports · 2020Observational
- A New Hypothesis on Anxiety, Sleep Insufficiency, and Viral Infections; Reciprocal Links to Consider in Today's "World vs. COVID-19" Endeavors.Frontiers in psychiatry · 2020Review
- Review
- Fruit-Derived Polyphenol Supplementation for Athlete Recovery and Performance.Sports medicine (Auckland, N.Z.) · 2019Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveIn the present work, we evaluated the effect of the intake of a Jerte Valley cherry-based product (JVCP), compared to a placebo product, on sleep quality, urinary 6-sulfatoxymelatonin (aMT6-s) levels and the serum concentration of interleukin-1β (IL-1β), tumor necrosis factor α (TNF-α) and interleukin-8 (IL-8).
designThis was a blind, placebo-controlled, randomized, crossover study.
settingUniversity of Extremadura (Spain).
participantsTen young (20-30 years old), ten middle-aged (35-55 years old), and ten elderly (65-85 years old) participants.
interventionA placebo (Kool-Aid®) or JVCP (patent no. ES 2342141 B1) were consumed twice a day, as lunch and dinner desserts. MEASUREMENTS: Actigraphic monitoring was used to record and display the temporal patterns of the individuals' activity and rest. Urinary aMT6-s and serum cytokines (IL-1β, TNF-α and IL-8) were also determined.
resultsThe consumption of the JVCP improved the nocturnal rest, measured by sleep efficiency, number of awakenings, total nocturnal activity, sleep latency, assumed sleep, actual sleep time and immobility. Moreover, it was detected an increase in both the levels of aMT6-s found in first-void morning urine and the concentrations of serum pro-somnogenic cytokines obtained from samples collected at the acrophase of the melatonin rhythm (1.00 am) in all experimental age groups after the JVCP consumption. Generally, better results were obtained with advancing age.
conclusionThe ingestion of the JVCP may contribute to establish a high-quality sleep and be used as a potential nutraceutical tool to prevent sleep disorders with the advance of age.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.