SynthesisFunctional neurology
The effectiveness of habit reversal therapy in the treatment of Tourette syndrome and other chronic tic disorders: a systematic review.
Synthesis in Functional neurology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03621059 (Behavioral Therapy for Children and Adolescents With Tourette Syndrome), which is not on this map. Cited by 32 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Behavioral Therapy for Children and Adolescents With Tourette Syndrome: A Randomized Controlled Trial in Taiwan
Who cites it
32 citing papers in PubMed, 4 syntheses or guidelines pooled it, 99 citations in OpenAlex.
- Safety and Efficacy of Ecopipam in Patients with Tourette Syndrome: A Systematic Review and Meta-analysis.CNS drugs · 2025Pooled it
- Systematic review-understanding the barriers and facilitators experienced by healthcare professionals in providing care for tics: a mixed methods systematic review of clinical knowledge, attitudes, and practices.BMC medical education · 2024Pooled it
- Non-invasive brain stimulation as therapy: systematic review and recommendations with a focus on the treatment of Tourette syndrome.Experimental brain research · 2022Pooled it
- The prevalence of tic disorders for children in China: A systematic review and meta-analysis.Medicine · 2016Pooled it
- Retraining and control therapy for pediatric psychogenic non-epileptic seizures.Annals of clinical and translational neurology · 2020Trial
- Randomized, Double-Blind, Placebo-Controlled Trial Demonstrates the Efficacy and Safety of Oral Aripiprazole for the Treatment of Tourette's Disorder in Children and Adolescents.Journal of child and adolescent psychopharmacology · 2017Trial
- What can clinical disorders involving the basal ganglia tell us about the pathophysiology of obsessive and compulsive symptoms?Journal of neural transmission (Vienna, Austria : 1996) · 2026Review
- From Pharmacological Treatment to Neuromodulation: A Comprehensive Approach to Managing Gilles de la Tourette Syndrome.International journal of molecular sciences · 2025Review
- Combined Habit Reversal Therapy and Acceptance and Commitment Therapy for Treatment of Tics in Tourette Syndrome: A Pilot Study of Effectiveness and Response Duration.Movement disorders clinical practice · 2025Article
- Symptom Network Analysis in a Large Sample of Children and Adults with a Chronic Tic Disorder.Movement disorders clinical practice · 2024Article
- State of the Evidence for Use of Psychotropic Medications in School-Age Youth.Children (Basel, Switzerland) · 2023Review
- Premonitory Urge and Tic Severity, Comorbidities, and Quality of Life in Chronic Tic Disorders.Movement disorders clinical practice · 2023Article
- Cognitive and Neural Mechanisms of Behavior Therapy for Tics: A Perception-Action Integration Approach.Biomedicines · 2023Review
- Enhanced habit formation in Tourette patients explained by shortcut modulation in a hierarchical cortico-basal ganglia model.Brain structure & function · 2022Article
- "Don't Touch Your Face!" The Contribution of Habit Reversal in the COVID-19 Pandemic.Health psychology research · 2022Article
- Protocol of a randomized controlled trial to investigate the efficacy and neural correlates of mindfulness-based habit reversal training in children with Tourette syndrome.Frontiers in psychiatry · 2022Article
- A Review of Cognitive and Behavioral Interventions for Tic Disorder.Soa--ch'ongsonyon chongsin uihak = Journal of child & adolescent psychiatry · 2021Article
- The Premonitory Urge for Tics Scale in a large sample of children and adolescents: psychometric properties in a developmental context. An EMTICS study.European child & adolescent psychiatry · 2020Article
- Children from nuclear families with bad parental relationship could develop tic symptoms.Molecular genetics & genomic medicine · 2020Article
- Review of habit reversal training for tic disorders.Pediatric investigation · 2020Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Tourette syndrome (TS) is a neurodevelopmental disorder characterized by multiple tics, which can require active intervention. It is recognized that behavioral techniques, especially habit reversal therapy (HRT), can offer an effective alternative or complement to pharmacotherapy in this setting. We conducted a systematic literature review to evaluate the efficacy of HRT in TS and other chronic tic disorders (CTDs). Our search was restricted to randomized controlled trials that used standardized diagnostic and outcome measures to compare the efficacy of HRT against a control treatment. We identified five relevant studies, which included 353 patients. Significant post-treatment reductions in tic severity scores (range: 18.3%-37.5%) were seen in the HRT groups across all studies. Current evidence suggests that HRT can significantly reduce tic severity in both adults and children with TS and other CTDs. Further head-to-head studies are needed to compare the efficacy of HRT with other behavioral interventions for tic management.
Indexed as
Identifiers
23731910PMC3812724W615670918What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.