Evidence map›Paper›PMID 23731854›Full record

ArticleJournal of translational medicine2013

Future perspectives in melanoma research. Meeting report from the "Melanoma Bridge. Napoli, December 2nd-4th 2012".

Paolo A Ascierto, Antonio M Grimaldi, Nicolas Acquavella, Lorenzo Borgognoni, Luana Calabrò, Natale Cascinelli, Alessandra Cesano, Michele Del Vecchio, Alexander M Eggermont, Mark Faries and 28 more

Open access · goldAbstract readConference Proceedings
In one paragraph

Article in Journal of translational medicine, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 18 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Naringin suppresses the metabolism of A375 cells by inhibiting the phosphorylation of c-Src.Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine · 2016
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

38 authors at 20 institutions in 11 countries.

Paolo A AsciertoIstituto Nazionale Tumori, Fondazione "G, Pascale", Naples, Italy. paolo.ascierto@gmail.com
Antonio M Grimaldi
Nicolas Acquavella
Lorenzo Borgognoni
Luana Calabrò
Natale Cascinelli
Alessandra Cesano
Michele Del Vecchio
Alexander M Eggermont
Mark Faries
Soldano Ferrone
Bernard A Fox
Thomas F Gajewski
Jérôme Galon
Sacha Gnjatic
Helen Gogas
Mohammed Kashani-Sabet
Howard L Kaufman
James Larkin
Roger S Lo
Alberto Mantovani
Kim Margolin
Cornelis Melief
Grant McArthur
Giuseppe Palmieri
Igor Puzanov
Antoni Ribas
Barbara Seliger
Jeff Sosman
Peter Suenaert
Ahmad A Tarhini
Giorgio Trinchieri
Fernando Vidal-Vanaclocha
Ena Wang
Gennaro Ciliberto
Nicola Mozzillo
Francesco M Marincola
Magdalena Thurin
Istituto Nazionale Tumori IRCCS "Fondazione G. Pascale" · ITUniversity of California, Los Angeles · USCalifornia Pacific Medical Center · USCenter for Cancer Research · USDélégation Paris 5 · FRFondazione IRCCS Istituto Nazionale dei Tumori · ITGlaxoSmithKline (Belgium) · BEHarvard University · USHumanitas University · ITIcahn School of Medicine at Mount Sinai · USInstitut Gustave Roussy · FRLeiden University Medical Center · NLMartin Luther University Halle-Wittenberg · DENational and Kapodistrian University of Athens · GRNational Institutes of Health · USNational Research Council · ITNodality (United States) · USOregon Health & Science University · USPeter MacCallum Cancer Centre · AURoyal Marsden NHS Foundation Trust · GB

Funding

Role of inflammation, innate resistance, and immunity in carcinogenesis.ZIABC010793 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI TRINCHIERI, GIORGIO · 2009 to 2025
$16.8M
6 · The paper itself

Abstract

Recent insights into the genetic and somatic aberrations have initiated a new era of rapidly evolving targeted and immune-based treatments for melanoma. After decades of unsuccessful attempts to finding a more effective cure in the treatment of melanoma now we have several drugs active in melanoma. The possibility to use these drugs in combination to improve responses to overcome the resistance, to potentiate the action of immune system with the new immunomodulating antibodies, and identification of biomarkers that can predict the response to a particular therapy represent new concepts and approaches in the clinical management of melanoma. The third "Melanoma Research: "A bridge from Naples to the World" meeting, shortened as "Bridge Melanoma Meeting" took place in Naples, December 2 to 4th, 2012. The four topics of discussion at this meeting were: advances in molecular profiling and novel biomarkers, combination therapies, novel concepts toward integrating biomarkers and therapies into contemporary clinical management of patients with melanoma across the entire spectrum of disease stage, and the knowledge gained from the biology of tumor microenvironment across different tumors as a bridge to impact on prognosis and response to therapy in melanoma. This international congress gathered more than 30 international faculty members who in an interactive atmosphere which stimulated discussion and exchange of their experience regarding the most recent advances in research and clinical management of melanoma patients.

Indexed as

AnimalsAntineoplastic AgentsBiomarkers, TumorClinical Trials as TopicGene Expression Regulation, NeoplasticHumansMedical OncologyMelanomaMutationPrognosisSkin NeoplasmsAntineoplastic AgentsBiomarkers, Tumor

Identifiers

PMID23731854
PMCPMC3681569
OpenAlexW4211065821

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.