ReviewThe FEBS journal2013
Engineered proteins with Pumilio/fem-3 mRNA binding factor scaffold to manipulate RNA metabolism.
Review in The FEBS journal, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
33 citing papers in PubMed.
- Inherent Specificity and Variation Sensitivity as Quantitative Metrics for RBP Binding.bioRxiv : the preprint server for biology · 2026Article
- A Method for Bioluminescence-Based RNA Monitoring Using Split-Luciferase Reconstitution Techniques.Methods in molecular biology (Clifton, N.J.) · 2025Article
- Engineering circular RNA for molecular and metabolic reprogramming.Functional & integrative genomics · 2024Review
- dCas12a:Pre-crRNA: A New Tool to Induce mRNA Degradation in Saccharomyces cerevisiae Synthetic Gene Circuits.Methods in molecular biology (Clifton, N.J.) · 2024Article
- Engineered deaminases as a key component of DNA and RNA editing tools.Molecular therapy. Nucleic acids · 2023Review
- Simultaneous multifunctional transcriptome engineering by CRISPR RNA scaffold.Nucleic acids research · 2023Article
- CRISPR-associated type V proteins as a tool for controlling mRNA stability in S. cerevisiae synthetic gene circuits.Nucleic acids research · 2023Article
- The Role of Pumilio RNA Binding Protein in Plants.Biomolecules · 2021Review
- Expanding the binding specificity for RNA recognition by a PUF domain.Nature communications · 2021Article
- 5'-UTR SNP ofeLife · 2021Article
- Engineering circular RNA regulators to specifically promote circular RNA production.Theranostics · 2021Article
- The potential of engineered eukaryotic RNA-binding proteins as molecular tools and therapeutics.Wiley interdisciplinary reviews. RNA · 2020Review
- Modulation of miRNA function by natural and synthetic RNA-binding proteins in cancer.Cellular and molecular life sciences : CMLS · 2019Review
- Functional and molecular characterization of the conserved Arabidopsis PUMILIO protein, APUM9.Plant molecular biology · 2019Article
- Article
- Expanding RNA binding specificity and affinity of engineered PUF domains.Nucleic acids research · 2018Article
- Substrate specificity of human MCPIP1 endoribonuclease.Scientific reports · 2018Article
- Structural basis for the specific recognition of 18S rRNA by APUM23.Nucleic acids research · 2017Article
- PUM1 is a biphasic negative regulator of innate immunity genes by suppressing LGP2.Proceedings of the National Academy of Sciences of the United States of America · 2017Article
- Targeted inhibition of oncogenic miR-21 maturation with designed RNA-binding proteins.Nature chemical biology · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
Pumilio/fem-3 mRNA binding factor proteins are characterized by a sequence-specific RNA-binding domain. This unique single-stranded RNA recognition module, whose sequence specificity can be reprogrammed, has been fused with functional modules to engineer protein factors with various functions. We summarize the advances made with respect to developing RNA regulatory tools, as well as opportunities for the future.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.