ArticleAsian Pacific journal of tropical biomedicine2013
Tegumental histological effects of Mirazid(®) and myrrh volatile oil on adult Fasciola gigantica.
Article in Asian Pacific journal of tropical biomedicine, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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2 citing papers in PubMed, 8 citations in OpenAlex.
- Efficacy of myrrh extract against Eimeria labbeana-like experimental infection in Columba livia domestica: in vivo study.BMC veterinary research · 2024Article
- Evaluation of anthelminthic and antiprotozoal activity of myrrh (Helminthologia · 2024Article
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5 authors at 1 institution in 1 country.
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Abstract
objectiveTo evaluated the histological changes within the tegument of adult Fasciola gigantica (F. gigantica) that led to the gross changes that were visible externally.
methodsThe effects of oleoresin extract of myrrh (Mirazid(®)), myrrh volatile oil and triclabendazole sulphoxide (reference drug) on the tegumental structure of adult F. gigantica following treatment in vitro had been determined by light microscopy.
resultsThe internal changes in the tegument observed in this study were compatible with surface changes seen in the previous scanning electron microscopy study, using the same drugs. The swelling of tegumental syncytium was a particular feature of their action, but its level was much greater with myrrh volatile oil, in which vacuolization of the tegument and loss of spines were observed.
conclusionsThe present study demonstrated the fasciocidal properties of Mirazid(®) oleoresin extract, and it might be possible to reinforce its fasciocidal activity by increasing its content of myrrh volatile oil.
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