ArticleAging and disease2013
The effects of aging and electrical stimulation exercise on bone after spinal cord injury.
Article in Aging and disease, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it, 30 citations in OpenAlex.
- Nutritional status in chronic spinal cord injury: a systematic review and meta-analysis.Spinal cord · 2019Pooled it
- The safety of epidural spinal cord stimulation to restore function after spinal cord injury: post-surgical complications and incidence of cardiovascular events.Spinal cord · 2022Trial
- Integration of functional electrical stimulation during robotic-assisted intervention to increase bone mineral density in individuals with complete spinal cord injury: case report.Spinal cord series and cases · 2024Article
- Review
- Electrical Stimulation Exercise for People with Spinal Cord Injury: A Healthcare Provider Perspective.Journal of clinical medicine · 2023Review
- Metastatic spine oncology: symptom-directed management.Neuro-oncology practice · 2020Article
- Bone changes in the lower limbs from participation in an FES rowing exercise program implemented within two years after traumatic spinal cord injury.The journal of spinal cord medicine · 2020Article
- Regular Muscle Electrical Stimulation Could Act Favorably On Bone Mineral Density in Healthy Aged Subjects.Frontiers in physiology · 2018Article
- The age factor in axonal repair after spinal cord injury: A focus on neuron-intrinsic mechanisms.Neuroscience letters · 2017Review
- A NovelBioMed research international · 2016Article
- Revisiting the Debate: Does Exercise Build Strong Bones in the Mature and Senescent Skeleton?Frontiers in physiology · 2016Article
- Activity-Based Restorative Therapies after Spinal Cord Injury: Inter-institutional conceptions and perceptions.Aging and disease · 2015Review
- Whole-Body Electromyostimulation to Fight Osteopenia in Elderly Females: The Randomized Controlled Training and Electrostimulation Trial (TEST-III).Journal of osteoporosis · 2015Article
- Improving the Efficiency of Electrical Stimulation Activities After Spinal Cord Injury.Current physical medicine and rehabilitation reports · 2014Article
- Musculoskeletal disorders in chronic obstructive pulmonary disease.BioMed research international · 2014Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Age related bone loss predisposes adults to osteoporosis. This is especially true for individuals with spinal cord injury (SCI). The effects of decreased bone loading with older age and paralysis significantly contribute to decreased bone mass and increased risk for fragility fractures. Loading bone via volitional muscle contractions or by using electrical stimulation are common methods for helping to prevent and/or decrease bone loss. However the effectiveness and safety of electrical stimulation activities remain unclear. The purpose of this review is to investigate the factors associated with aging and osteoporosis after SCI, the accuracy of bone measurement, the effects of various forms of bone loading activities with a focus on electrical stimulation activities and the safety of physical exercise with a focus on electrical stimulation cycling. Osteoporosis remains a disabling and costly condition for older adults and for those with paralysis. Both dual energy x-ray absorptiometry and peripheral quantitative computed tomography are valuable techniques for measuring bone mineral density (BMD) with the latter having the ability to differentiate trabecular and cortical bone. Physical activities have shown to be beneficial for increasing BMD however, the extent of the benefits related to aging and paralysis remain undetermined. Electrical stimulation activities administered appropriately are assumed safe due to thousands of documented safe FES cycling sessions. However, specific documentation is needed to verify safety and to development formal guidelines for optimal use.
Indexed as
Identifiers
23730530PMC3660124W1547125201What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.