Evidence map›Paper›PMID 23730253›Full record

ArticleCurrent neuropharmacology2012

Redox processes in neurodegenerative disease involving reactive oxygen species.

Peter Kovacic, Ratnasamy Somanathan

Abstract read
In one paragraph

Article in Current neuropharmacology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. In vivoScientific reports · 2020
    Article
  3. Article
  4. Article
  5. Extracellular superoxide dismutase and its role in cancer.Free radical biology & medicine · 2017
    Review
  6. Review
  7. Article
  8. Review
  9. Evidence of higher oxidative status in depression and anxiety.Oxidative medicine and cellular longevity · 2014
    Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Peter KovacicDepartment of Chemistry and Biochemistry, San Diego State University, San Diego CA 92182 USA.
Ratnasamy Somanathan

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Much attention has been devoted to neurodegenerative diseases involving redox processes. This review comprises an update involving redox processes reported in the considerable literature in recent years. The mechanism involves reactive oxygen species and oxidative stress, usually in the brain. There are many examples including Parkinson's, Huntington's, Alzheimer's, prions, Down's syndrome, ataxia, multiple sclerosis, Creutzfeldt-Jacob disease, amyotrophic lateral sclerosis, schizophrenia, and Tardive Dyskinesia. Evidence indicates a protective role for antioxidants, which may have clinical implications. A multifaceted approach to mode of action appears reasonable.

Indexed as

neurodegenerative diseasesoxidative stress.reactive oxygen speciesRedox

Identifiers

PMID23730253
PMCPMC3520039

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.