ArticleClinics in colon and rectal surgery2012
Extracolonic manifestations of lynch syndrome.
Article in Clinics in colon and rectal surgery, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
23 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Characterization of sebaceous and non-sebaceous cutaneous manifestations in patients with lynch syndrome: a systematic review.Familial cancer · 2023Pooled it
- Trial
- A Rare Case of Four Primary Tumors in a Patient With Lynch Syndrome.Clinical case reports · 2025Article
- Risk of lymphoid malignancy associated with cancer predisposition genes.Blood cancer journal · 2025Article
- The landscape of rare genetic variants in familial Waldenström macroglobulinemia.Blood neoplasia · 2024Article
- Review
- Case of Metastatic Pheochromocytoma and Meningiomas in a Patient With Lynch Syndrome.JCO precision oncology · 2022Article
- From Genetics to Histomolecular Characterization: An Insight into Colorectal Carcinogenesis in Lynch Syndrome.International journal of molecular sciences · 2021Review
- Diagnostics of Mutations in MMR/Diagnostics (Basel, Switzerland) · 2020Review
- Thymic cancer in lynch syndrome: an unusual association.BMJ case reports · 2020Article
- Primary malignant pericardial tumour in Lynch syndrome.BMC cancer · 2020Article
- Targeted sequencing of genes associated with the mismatch repair pathway in patients with endometrial cancer.PloS one · 2020Article
- En bloc resection of visceral aorta and right kidney due to aortic sarcoma using temporary extracorporeal bypass grafting.Journal of vascular surgery cases and innovative techniques · 2019Article
- Data on Single Nucleotide Polymorphism of DNA Repair Genes and Breast Cancer Risk from Poland.Pathology oncology research : POR · 2019Article
- Polymorphism of DNA repair genes in breast cancer.Oncotarget · 2019Article
- Solitary plasmacytoma of thoracic vertebra in a woman with Lynch syndrome: A case report.International journal of surgery case reports · 2019Article
- Association between single nucleotide polymorphism of DNA repair genes and endometrial cancer: a case-control study.International journal of clinical and experimental pathology · 2018Article
- Expending Role of Microsatellite Instability in Diagnosis and Treatment of Colorectal Cancers.Journal of gastrointestinal cancer · 2017Review
- Article
- Predispositions to Lymphoma: A Practical Review for Genetic Counselors.Journal of genetic counseling · 2016Review
Corrections and comments
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Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Lynch syndrome has classically been defined by several predominant malignancies. Initial clinical criteria for diagnosis of Lynch syndrome would miss 40% of affected individuals. As time has passed, our understanding of Lynch syndrome has evolved and will continue to do so. The number of cancer types that are included in the Lynch phenotype is growing. This has allowed clinicians to redefine Lynch syndrome, at risk populations, screening needs, and diagnostic criteria. Inclusion of extracolonic malignancies and alternative genetic pathways gives new insight into the true prevalence and penetrance of Lynch syndrome.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.