ReviewComprehensive physiology2012
Mechanics and function of the pulmonary vasculature: implications for pulmonary vascular disease and right ventricular function.
Review in Comprehensive physiology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
43 citing papers in PubMed.
- Pulsatile flow dynamics maintain pulmonary artery architecture.JCI insight · 2026Article
- Synchronization-Dissipation in the Cardiorespiratory System.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- A Lifelong Journey in the Field of the Pulmonary Circulation: Perspectives Through the Lens of the Cardiovascular Pulmonary Research Laboratory.Pulmonary circulation · 2025Article
- Pulmonary arterial compliance as a measure of right ventricular loading in mitral regurgitation.International journal of cardiology. Heart & vasculature · 2024Review
- Severe Acute Bronchial Asthma with Sepsis: Determining the Status of Biomarkers in the Diagnosis of the Disease.Diagnostics (Basel, Switzerland) · 2023Review
- The sine transform is theFrontiers in cardiovascular medicine · 2023Article
- A structural approach to 3D-printing arterial phantoms with physiologically comparable mechanical characteristics: Preliminary observations.Proceedings of the Institution of Mechanical Engineers. Part H, Journal of engineering in medicine · 2022Article
- Higher pulmonary vein index on computed angiography and optimum surgical resection ensures smooth postoperative recovery in Fallot's tetralogy: Special emphasis on indices of evaluation and Monocusp preparation.Clinical case reports · 2022Article
- Hemodynamically Unloading the Distal Pulmonary Circulation in Pulmonary Hypertension: A Modeling Study.Journal of biomechanical engineering · 2022Article
- Pulsatile pulmonary artery pressure in a large animal model of chronic thromboembolic pulmonary hypertension: Similarities and differences with human data.Pulmonary circulation · 2022Article
- Pulmonary hypertension: Linking inflammation and pulmonary arterial stiffening.Frontiers in immunology · 2022Review
- Pathophysiology of COVID-19: Critical Role of Hemostasis.Frontiers in cellular and infection microbiology · 2022Review
- Do alterations in pulmonary vascular tone result in changes in central blood volumes? An experimental study.Intensive care medicine experimental · 2021Article
- Basement Membrane Extracellular Matrix Proteins in Pulmonary Vascular and Right Ventricular Remodeling in Pulmonary Hypertension.American journal of respiratory cell and molecular biology · 2021Article
- Limited value of pulse wave analysis in assessing arterial wave reflection and stiffness in the pulmonary artery.Physiological reports · 2021Article
- Loss of Pulmonary Vascular Volume as a Predictor of Right Ventricular Dysfunction and Mortality in Acute Pulmonary Embolism.Circulation. Cardiovascular imaging · 2021Article
- Inverse modeling framework for characterizing patient-specific microstructural changes in the pulmonary arteries.Journal of the mechanical behavior of biomedical materials · 2021Article
- Potential damage in pulmonary arterial hypertension: An experimental study of pressure-induced damage of pulmonary artery.Journal of biomedical materials research. Part A · 2021Article
- The isobaric pulmonary arterial compliance in pulmonary hypertension.ERJ open research · 2021Article
- Echocardiographic assessment of pulmonary arterial capacitance predicts mortality in pulmonary hypertension.Journal of cardiology · 2021Article
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
he relationship between cardiac function and the afterload against which the heart muscle must work to circulate blood throughout the pulmonary circulation is defined by a complex interaction between many coupled system parameters. These parameters range broadly and incorporate system effects originating primarily from three distinct locations: input power from the heart, hydraulic impedance from the large conduit pulmonary arteries, and hydraulic resistance from the more distal microcirculation. These organ systems are not independent, but rather, form a coupled system in which a change to any individual parameter affects all other system parameters. The result is a highly nonlinear system which requires not only detailed study of each specific component and the effect of disease on their specific function, but also requires study of the interconnected relationship between the microcirculation, the conduit arteries, and the heart in response to age and disease. Here, we investigate systems-level changes associated with pulmonary hypertensive disease progression in an effort to better understand this coupled relationship.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.