Evidence map›Paper›PMID 23727557›Full record

ArticleAnalytical biochemistry2013

An electrochemiluminescence assay for gp340 (DMBT1).

Cheryl Barber, Drew Weissman, Kurt Barnhart, Minal Dalvi, William R Abrams, Daniel Malamud

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Analytical biochemistry, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 92% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Cheryl BarberDepartment of Basic Sciences, College of Dentistry, New York University, New York, NY 10010, USA.
Drew Weissman
Kurt Barnhart
Minal Dalvi
William R Abrams
Daniel Malamud
New York University · USUniversity of Pennsylvania · US

Funding

The Proteomic and Functional Profile of HIV Positive SalivaU19DE018385 · NIDCR · NEW YORK UNIVERSITY · PI MALAMUD, DANIEL · 2007 to 2014
$6.6M
The Role of Scavenger Receptor gp340 in Mucosal HIV-1 Transmission and InhibitionR01AI094599 · NIAID · UNIV OF MED/DENT OF NJ-NJ MEDICAL SCHOOL · PI LU, MIN, MALAMUD, DANIEL · 2011 to 2016
$3.9M
Gp340 and syndecan inhibition based microbicide for HIVR33AI082701 · NIAID · UNIVERSITY OF PENNSYLVANIA · PI WEISSMAN, DREW · 2012 to 2014
$1.4M
Gp340 and syndecan inhibition based microbicide for HIVR21AI082701 · NIAID · UNIVERSITY OF PENNSYLVANIA · PI WEISSMAN, DREW · 2009 to 2010
$437k
NIAID NIH HHS AI082701NIAID NIH HHS AI094599-01NIAID NIH HHS R01 AI094599NIAID NIH HHS R21 AI082701NIAID NIH HHS R33 AI082701NIDCR NIH HHS U19 DE018385NIDCR NIH HHS U19DE018385
6 · The paper itself

Abstract

Gp340 is a member of the scavenger receptor cysteine-rich family of innate immune molecules and also functions as a tumor suppressor. This study describes a picogram-level assay using electrochemiluminescence technology on the MesoScale Discovery platform. Antibodies were evaluated and the best pair was used to assay whole-mouth stimulated saliva and cervical/vaginal lavage. The assay was tested using specimens obtained from healthy volunteers to determine if gp340 concentration in saliva correlates with levels in vaginal lavage fluid. Interestingly, no correlation was determined between gp340 content in these two fluids.

Indexed as

Calcium-Binding ProteinsDNA-Binding ProteinsElectrochemical TechniquesEnzyme-Linked Immunosorbent AssayFemaleHumansLuminescent MeasurementsMaleReceptors, Cell SurfaceReceptors, ScavengerSalivaSensitivity and SpecificityTumor Suppressor ProteinsVaginal DouchingCalcium-Binding ProteinsDMBT1 protein, humanDNA-Binding ProteinsReceptors, Cell SurfaceReceptors, ScavengerTumor Suppressor ProteinsCervical vaginal lavageMesoScale DiscoverySalivary agglutininScavenger receptor cysteine-richWhole-mouth stimulated saliva

Identifiers

PMID23727557
PMCPMC3719401
OpenAlexW1999651498

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.