ArticleNeuroImage2013
Spatial-temporal atlas of human fetal brain development during the early second trimester.
Article in NeuroImage, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 1 of them a synthesis that pooled it.
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Who cites it
35 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Novel imaging techniques to study postmortem human fetal anatomy: a systematic review on microfocus-CT and ultra-high-field MRI.European radiology · 2020Pooled it
- Imaging of Embryonic and Fetal Brain Development Using MRI Microscopy: Achieving High Spatial Resolution.Medical sciences (Basel, Switzerland) · 2026Review
- Equivariant Symmetry-Aware Head Pose Estimation for Fetal MRI.Computer vision - ECCV ... : ... European Conference on Computer Vision : proceedings. European Conference on Computer Vision · 2026Article
- Analysis of automatic fetal intracranial volume (ICV) measurement based on the optimized ultrasound Smart ICV method at 16-34 weeks of gestation.Quantitative imaging in medicine and surgery · 2024Article
- Maternal hsa-miR-423-5p associated with the cognitive development of babies in pregnant women without mental disorders.Frontiers in human neuroscience · 2024Article
- Fetal Brain Growth in the Early Second Trimester.AJNR. American journal of neuroradiology · 2023Observational
- Neuromorphological Atlas of Human Prenatal Brain Development: White Paper.Life (Basel, Switzerland) · 2023Article
- Spatiotemporal Atlas of the Fetal Brain Depicts Cortical Developmental Gradient.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2022Article
- Changes in and asymmetry of the proteome in the human fetal frontal lobe during early development.Communications biology · 2022Article
- Automated detection and reacquisition of motion-degraded images in fetal HASTE imaging at 3 T.Magnetic resonance in medicine · 2022Article
- Measuring decline in white matter integrity after systemic treatment for breast cancer: omitting skeletonization enhances sensitivity.Brain imaging and behavior · 2021Article
- Early development of human ganglionic eminences assessedMedicine and pharmacy reports · 2021Article
- A spatio-temporal atlas of the developing fetal brain with spina bifida aperta.Open research Europe · 2021Article
- Morphometric development of the human fetal cerebellum during the early second trimester.NeuroImage · 2020Article
- Anatomical and diffusion MRI brain atlases of the fetal rhesus macaque brain at 85, 110 and 135 days gestation.NeuroImage · 2020Article
- Review
- Research Advances of Germinal Matrix Hemorrhage: An Update Review.Cellular and molecular neurobiology · 2019Review
- Fetal ocular development in the second trimester of pregnancy documented by 7.0 T postmortem Magnetic Resonance Imaging.PloS one · 2019Article
- Visualization of the periventricular Virchow-Robin spaces with ependymal openings.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2018Article
- Fetal neuroimaging: an update on technical advances and clinical findings.Pediatric radiology · 2018Review
Corrections and comments
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Authors and funding
15 authors.
Funding
Abstract
During the second trimester, the human fetal brain undergoes numerous changes that lead to substantial variation in the neonatal in terms of its morphology and tissue types. As fetal MRI is more and more widely used for studying the human brain development during this period, a spatiotemporal atlas becomes necessary for characterizing the dynamic structural changes. In this study, 34 postmortem human fetal brains with gestational ages ranging from 15 to 22 weeks were scanned using 7.0 T MR. We used automated morphometrics, tensor-based morphometry and surface modeling techniques to analyze the data. Spatiotemporal atlases of each week and the overall atlas covering the whole period with high resolution and contrast were created. These atlases were used for the analysis of age-specific shape changes during this period, including development of the cerebral wall, lateral ventricles, Sylvian fissure, and growth direction based on local surface measurements. Our findings indicate that growth of the subplate zone is especially striking and is the main cause for the lamination pattern changes. Changes in the cortex around Sylvian fissure demonstrate that cortical growth may be one of the mechanisms for gyration. Surface deformation mapping, revealed by local shape analysis, indicates that there is global anterior-posterior growth pattern, with frontal and temporal lobes developing relatively quickly during this period. Our results are valuable for understanding the normal brain development trajectories and anatomical characteristics. These week-by-week fetal brain atlases can be used as reference in in vivo studies, and may facilitate the quantification of fetal brain development across space and time.
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