ArticleNeuroscience2013
A spontaneous state of weakly correlated synaptic excitation and inhibition in visual cortex.
Article in Neuroscience, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 22 citations in OpenAlex.
- Subthreshold moment analysis of neuronal populations driven by synchronous synaptic inputs.PLoS computational biology · 2025Article
- Subthreshold moment analysis of neuronal populations driven by synchronous synaptic inputs.ArXiv · 2025Article
- Subthreshold variability of neuronal populations driven by synchronous synaptic inputs.bioRxiv : the preprint server for biology · 2025Article
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- Efficient coding in biophysically realistic excitatory-inhibitory spiking networks.bioRxiv : the preprint server for biology · 2025Article
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- Heterogeneous mechanisms for synchronization of networks of resonant neurons under different E/I balance regimes.Frontiers in network physiology · 2022Article
- Network and cellular mechanisms underlying heterogeneous excitatory/inhibitory balanced states.The European journal of neuroscience · 2020Article
- Article
- Efficient codes and balanced networks.Nature neuroscience · 2016Review
- Simultaneous Bayesian Estimation of Excitatory and Inhibitory Synaptic Conductances by Exploiting Multiple Recorded Trials.Frontiers in computational neuroscience · 2016Article
- Exact Analysis of the Subthreshold Variability for Conductance-Based Neuronal Models with Synchronous Synaptic Inputs.Physical review. XArticle
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
Cortical spontaneous activity reflects an animal's behavioral state and affects neural responses to sensory stimuli. The correlation between excitatory and inhibitory synaptic input to single neurons is a key parameter in models of cortical circuitry. Recent measurements demonstrated highly correlated synaptic excitation and inhibition during spontaneous "up-and-down" states, during which excitation accounted for approximately 80% of inhibitory variance (Shu et al., 2003; Haider et al., 2006). Here we report in vivo whole-cell estimates of the correlation between excitation and inhibition in the rat visual cortex under pentobarbital anesthesia, during which up-and-down states are absent. Excitation and inhibition are weakly correlated, relative to the up-and-down state: excitation accounts for less than 40% of inhibitory variance. Although these correlations are lower than when the circuit cycles between up-and-down states, both behaviors may arise from the same circuitry. Our observations provide evidence that different correlational patterns of excitation and inhibition underlie different cortical states.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.