ArticleSchizophrenia research2013
Computerized facial analysis for understanding constricted/blunted affect: initial feasibility, reliability, and validity data.
Article in Schizophrenia research, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
24 citing papers in PubMed.
- Oxytocin-induced increase in N,N-dimethylglycine and time course of changes in oxytocin efficacy for autism social core symptoms.Molecular autism · 2021Trial
- The effects of oxytocin and galantamine on objectively-defined vocal and facial expression: Data from the CIDAR study.Schizophrenia research · 2017Trial
- Humanizing "multimodal" digital phenotyping of serious mental illness.Journal of psychopathology and clinical science · 2026Article
- Computerized assessments of emotional expression and emotional reactivity predict negative symptoms in individuals at clinical high-risk for psychosis.Psychological medicine · 2026Article
- Facial expressions and emotional experience during social interaction in autism and schizophrenia.Schizophrenia (Heidelberg, Germany) · 2026Article
- Emotion-specific vocabulary is associated with preschoolers' emotion knowledge and behavioral emotion regulation.Scientific reports · 2026Article
- Environmental deprivation is associated with reward processing impairments and negative symptoms in schizophrenia.Schizophrenia research · 2025Article
- Facial Emotional Expression in Reaction to Internet Gaming Videos Among Young Adults: A Preliminary and Exploratory Study.Neuropsychopharmacology reports · 2025Article
- Exploring emotion recognition in patients with mild cognitive impairment and Alzheimer's dementia undergoing a rehabilitation programPloS one · 2025Article
- The management of patients with predominant negative symptoms in Slovakia: A 1-year longitudinal, prospective, multicentric cohort study.European psychiatry : the journal of the Association of European Psychiatrists · 2024Article
- Positive Emotional Responses to Socially Assistive Robots in People With Dementia: Pilot Study.JMIR aging · 2024Article
- Clues from caregiver emotional language usage highlight the link between putative social environment and the psychosis-risk syndrome.Schizophrenia research · 2023Article
- Alterations in facial expressions of emotion: Determining the promise of ultrathin slicing approaches and comparing human and automated coding methods in psychosis risk.Emotion (Washington, D.C.) · 2022Article
- Racial and Ethnic Biases in Computational Approaches to Psychopathology.Schizophrenia bulletin · 2022Article
- Computerized analysis of facial expressions in serious mental illness.Schizophrenia research · 2022Article
- Using machine learning of computerized vocal expression to measure blunted vocal affect and alogia.NPJ schizophrenia · 2020Article
- Alterations in facial expressivity in youth at clinical high-risk for psychosis.Journal of abnormal psychology · 2019Article
- Computer-analyzed facial expression as a surrogate marker for autism spectrum social core symptoms.PloS one · 2018Article
- Greater ability to express positive emotion is associated with lower projected cardiovascular disease risk.Journal of behavioral medicine · 2017Article
- Paradigms for Assessing Hedonic Processing and Motivation in Humans: Relevance to Understanding Negative Symptoms in Psychopathology.Schizophrenia bulletin · 2017Review
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
Diminished expression is a diagnostic feature of a range of schizophrenia-spectrum disorders/conditions and is often unresponsive to treatment, is present across premorbid, first episode and various clinical states, and is considered a poor prognostic indicator. Surprisingly, little is known about diminished expression. The present study sought to address this issue by evaluating a commercially-available computerized facial analysis software for understanding diminished expressivity. We analyzed natural facial expression from a series of laboratory interaction tasks in 28 individuals with psychometric schizotypy - defined as the personality organization reflecting a putative genetic schizophrenia liability, and 26 matched controls. We evaluated (a) feasibility - defined in terms of the number of video frames recognized by the software, (b) reliability - defined in terms of correlations between facial expression variables across the three laboratory interactions, and (c) construct validity - defined in terms of relationships to clinical variables. For most subjects (~80%), approximately three-quarters of the video frames were analyzable by the software; however, a minority of the videos were essentially unreadable. The facial expression variables showed excellent reliability across interaction conditions. In terms of construct validity, facial expression variables were significantly related to a measure of psychoticism, tapping subjective cognitive concerns and "first-rank" schizophrenia symptoms, but were generally not different between groups. Facial expression variables were generally not significantly related to measures of depression, anxiety, paranoia or, surprisingly, self-reported negative schizotypy. While computerized facial analysis appears to be a reliable and promising method of understanding diminished expressivity across the schizophrenia-spectrum, some work remains. Implications are discussed.
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