Evidence map›Paper›PMID 23726184›Full record

ArticleJournal of biomechanics2013

Ultrasonic characterization of the nonlinear properties of canine livers by measuring shear wave speed and axial strain with increasing portal venous pressure.

Veronica Rotemberg, Brett Byram, Mark Palmeri, Michael Wang, Kathryn Nightingale

Open access · greenAbstract read
In one paragraph

Article in Journal of biomechanics, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.4field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
  2. Article
  3. Observational
  4. Article
  5. Article
  6. Changes in shear wave speed pre- and post-induction of labor: a feasibility study.Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology · 2015
    Article
  7. Article
  8. Ultrasound Shear Wave Simulation of Breast Tumor Using Nonlinear Tissue Elasticity.Computational and mathematical methods in medicine · 2015
    Article
  9. Ultrasound shear wave elastography helps discriminate low-grade from high-grade bowel wall fibrosis in ex vivo human intestinal specimens.Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine · 2014
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Veronica RotembergDepartment of Biomedical Engineering, Duke University, Room 136 Hudson Hall, Box 90281, Durham, NC 27708, USA. veronica.rotemberg@duke.edu
Brett Byram
Mark Palmeri
Michael Wang
Kathryn Nightingale
Duke University · USDuke Medical Center · US

Funding

Acoustic Radiation Force Impulse (ARFI) Imaging of Cardiac TissueR37HL096023 · NHLBI · DUKE UNIVERSITY · PI TRAHEY, GREGG E. · 2009 to 2018
$5.2M
REMOTE PALPATION IMAGING IN THE BREASTR01EB002132 · NIBIB · DUKE UNIVERSITY · PI NIGHTINGALE, KATHRYN RADABAUGH · 2003 to 2015
$4.9M
Radiation Force Imaging of Prostate Cancer and Guidance of Biopsy ProceduresR01CA142824 · NCI · DUKE UNIVERSITY · PI NIGHTINGALE, KATHRYN RADABAUGH · 2010 to 2021
$4.4M
Quantifying Cervical Softness with Elasticity ImagingR21HD063031 · NICHD · UNIVERSITY OF WISCONSIN-MADISON · PI FELTOVICH, HELEN, HALL, TIMOTHY J · 2010 to 2011
$415k
Assessing Use of Acoustic Radiation Force to Noninvasively Measure Liver PressureF30DK095544 · NIDDK · DUKE UNIVERSITY · PI ROTEMBERG, VERONICA MIRIAM · 2012 to 2013
$63k
NCI NIH HHS R01 CA142824NCI NIH HHS R01CA-142824NHLBI NIH HHS R37 HL096023NIBIB NIH HHS R01 EB-002132NIBIB NIH HHS R01 EB002132NICHD NIH HHS R21 HD063031NICHD NIH HHS R21HD063031NIDDK NIH HHS F30 DK095544NIDDK NIH HHS F30DK095544PHS HHS R37-H2096023
6 · The paper itself

Abstract

Elevated hepatic venous pressure is the primary source of complications in advancing liver disease. Ultrasound imaging is ideal for potential noninvasive hepatic pressure measurements as it is widely used for liver imaging. Specifically, ultrasound based stiffness measures may be useful for clinically monitoring pressure, but the mechanism by which liver stiffness increases with hepatic pressure has not been well characterized. This study is designed to elucidate the nonlinear properties of the liver during pressurization by measuring both hepatic shear wave speed (SWS) and strain with increasing pressure. Tissue deformation during hepatic pressurization was tracked in 8 canine livers using successively acquired 3-D B-mode volumes and compared with concurrently measured SWS. When portal venous pressure was increased from clinically normal (0-5mmHg) to pressures representing highly diseased states at 20mmHg, the liver was observed to expand with axial strain measures up to 10%. At the same time, SWS estimates were observed to increase from 1.5-2m/s at 0-5mmHg (baseline) to 3.25-3.5m/s at 20mmHg.

Indexed as

AnimalsBiomechanical PhenomenaDogsLiverLiver CirculationModels, CardiovascularNonlinear DynamicsPortal PressurePortal VeinUltrasonographyVascular StiffnessAcoustic radiation force impulse (ARFI)Hepatic pressureNonlinear mechanicsShear wave speed

Identifiers

PMID23726184
PMCPMC3812539
OpenAlexW2011374458

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.