Evidence map›Paper›PMID 23725972›Full record

SynthesisAmerican journal of kidney diseases : the official journal of the National Kidney Foundation2013

Comparison of life participation activities among adults treated by hemodialysis, peritoneal dialysis, and kidney transplantation: a systematic review.

Tanjala S Purnell, Priscilla Auguste, Deidra C Crews, Julio Lamprea-Montealegre, Temitope Olufade, Raquel Greer, Patti Ephraim, Johanna Sheu, Daniel Kostecki, Neil R Powe and 3 more

Open access · greenAbstract readComparative StudySystematic Review
In one paragraph

Synthesis in American journal of kidney diseases : the official journal of the National Kidney Foundation, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 120 papers, 8 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
120citing papers in PubMed, 8 pooled it
8.5field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

120 citing papers in PubMed, 8 syntheses or guidelines pooled it, 283 citations in OpenAlex.

  1. Pooled it
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  5. Examining post-donation outcomes in Hispanic/Latinx living kidney donors in the United States: A systematic review.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2022
    Pooled it
  6. Patient-reported outcome measures for life participation in peritoneal dialysis: a systematic review.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2021
    Pooled it
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  8. Guideline
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  19. Differences between xenotransplantation and allogeneic kidney transplantation: the current situation and future challenges in Japan.Journal of artificial organs : the official journal of the Japanese Society for Artificial Organs · 2025
    Review
  20. Article

60 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 1 country.

Tanjala S PurnellDivision of General Internal Medicine, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD; Welch Center for Prevention, Epidemiology, and Clinical Research, Johns Hopkins Medical Institutions, Baltimore, MD. Electronic address: tpurnel1@jhmi.edu.
Priscilla Auguste
Deidra C Crews
Julio Lamprea-Montealegre
Temitope Olufade
Raquel Greer
Patti Ephraim
Johanna Sheu
Daniel Kostecki
Neil R Powe
Hamid Rabb
Bernard Jaar
L Ebony Boulware
Johns Hopkins University · USHarvard University · USJohns Hopkins Medicine · USUniversity of California, San Francisco · US

Funding

Institute for Clinical and Translational Research (KL2)KL2RR025006 · NCRR · JOHNS HOPKINS UNIVERSITY · PI FORD, DANIEL ERNEST · 2007 to 2011
$12.9M
PATIENT ORIENTED RESEARCH IN KIDNEY DISEASEK24DK002643 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI POWE, NEIL R. · 1999 to 2009
$1.4M
Information and Financial Interventions for Kidney Donation in African AmericansR01DK079682 · NIDDK · JOHNS HOPKINS UNIVERSITY · PI BOULWARE, LEIGH E · 2007 to 2011
$1.3M
Clinical and Behavioral Determinants of CKD DisparitiesK23DK070757 · NIDDK · JOHNS HOPKINS UNIVERSITY · PI BOULWARE, LEIGH E · 2006 to 2010
$724k
Improving Primary Care to Narrow Racial Disparities in Chronic Kidney DiseaseK23DK094975 · NIDDK · JOHNS HOPKINS UNIVERSITY · PI GREER, RAQUEL CHARLES · 2012 to 2015
$722k
Race, Socioeconomic Status, Diet and Chronic Kidney DiseaseK23DK097184 · NIDDK · JOHNS HOPKINS UNIVERSITY · PI CREWS, DEIDRA CANDICE · 2013 to 2016
$684k
Financial Risks and Ethnic/Racial Disparities in Live Kidney DonationF31DK084840 · NIDDK · JOHNS HOPKINS UNIVERSITY · PI PURNELL, TANJALA · 2009 to 2011
$119k
NCRR NIH HHS 5KL2RR025006NCRR NIH HHS KL2 RR025006NIDDK NIH HHS F31 DK084840NIDDK NIH HHS F31DK084840NIDDK NIH HHS K23 DK070757NIDDK NIH HHS K23DK070757NIDDK NIH HHS K23 DK094975NIDDK NIH HHS K23 DK097184NIDDK NIH HHS K24 DK002643NIDDK NIH HHS K24DK02643NIDDK NIH HHS R01 DK079682NIDDK NIH HHS R01DK079682
6 · The paper itself

Abstract

backgroundA comprehensive assessment of the association of patients' renal replacement therapy (RRT) modality with their participation in life activities (physical function, travel, recreation, freedom, and work) is needed. STUDY

designSystematic review of peer-reviewed published studies. SETTING & POPULATION: Adults undergoing RRT (hemodialysis, peritoneal dialysis, or transplantation). SELECTION CRITERIA FOR STUDIES: We searched PubMed, Cochrane Library, and EMBASE from January 1980 through April 2012 for English-language articles that compared participation in life activities among patients receiving: (1) hemodialysis compared with peritoneal dialysis, (2) hemodialysis compared with kidney transplantation, or (3) peritoneal dialysis compared with kidney transplantation. PREDICTOR: RRT modality. OUTCOMES: Reported rates of physical function, travel, recreation, freedom, and work-related activities by RRT modality.

results46 studies (6 prospective cohort, 38 cross-sectional, and 2 pre-post transplantation) provided relevant comparisons of life participation activities among patients treated with hemodialysis, peritoneal dialysis, and kidney transplantation. Studies were conducted in 1985-2011 among diverse patient populations in 16 distinct locations. A majority of studies reported greater life participation rates for patients with kidney transplants compared with patients receiving either hemodialysis or peritoneal dialysis. In contrast, a majority of studies reported no differences in outcomes between patients receiving hemodialysis and patients receiving peritoneal dialysis. These results were consistent throughout the study period, across diverse populations, and among the subset of studies that performed appropriate adjustments for potential confounding factors. LIMITATIONS: Many studies included in the review had significant design weaknesses.

conclusionsEvidence suggests that patients with kidney transplants may experience better rates of life participation compared with patients receiving dialysis, whereas patients receiving hemodialysis and patients receiving peritoneal dialysis may experience similar rates of life participation. Rigorously performed studies are needed to better inform patients about the association of RRT with these important patient-reported outcomes.

Indexed as

Kidney TransplantationPeritoneal DialysisRenal DialysisAdultAgedAged, 80 and overFemaleHumansKidney Failure, ChronicMaleMiddle AgedOutcome Assessment, Health CareQuality of LifeRenal Replacement TherapySocial ParticipationTreatment OutcomeDialysisend-stage renal disease (ESRD) treatmentkidney transplantationphysical functioningquality of lifesocial participation

Identifiers

PMID23725972
PMCPMC3809150
OpenAlexW2132571607

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.