Evidence map›Paper›PMID 23725656›Full record

ReviewCurrent opinion in immunology2013

Human dendritic cell subsets in vaccination.

Karolina Palucka, Jacques Banchereau

Abstract readReview
In one paragraph

Review in Current opinion in immunology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed.

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  14. Distinct features of dendritic cell-based immunotherapy as cancer vaccines.Clinical and experimental vaccine research · 2018
    Review
  15. The Efficacy of CIK-Based Immunotherapies for Advanced Solid Tumors.Technology in cancer research & treatment · 2017
    Article
  16. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Karolina PaluckaRalph M. Steinmann Center for Cancer Vaccines, Baylor Institute for Immunology Research, Baylor Research Institute, Dallas, TX, USA. karolinp@baylorhealth.edu
Jacques Banchereau

Funding

Targeting Dendritic Cells for Enhanced Musocal ImmunityU19AI057234 · NIAID · BAYLOR RESEARCH INSTITUTE · PI RAMILO, OCTAVIO · 2003 to 2013
$49.2M
Induction of melanoma immunity by dendritic cell subsetsP01CA084512 · NCI · ROCKEFELLER UNIVERSITY · PI BANCHEREAU, JACQUES F · 2000 to 2010
$12.1M
SUBPOPULATIONS OF HUMAN DENDRITIC CELLSR01CA078846 · NCI · BAYLOR RESEARCH INSTITUTE · PI BANCHEREAU, JACQUES F · 1999 to 2008
$2.5M
Vaccination with IL-15 DC to Generate Melanoma-specific Protective Memory T CellsR01CA140602 · NCI · BAYLOR RESEARCH INSTITUTE · PI PALUCKA, ANNA KAROLINA · 2010 to 2013
$1.4M
Dendritic Cells and Breast Cancer ImmunityR01CA089440 · NCI · BAYLOR RESEARCH INSTITUTE · PI PALUCKA, ANNA KAROLINA · 2001 to 2004
$930k
NCI NIH HHS CA078846NCI NIH HHS CA140602NCI NIH HHS P01 CA084512NCI NIH HHS P01 CA084514NCI NIH HHS R01 CA078846NCI NIH HHS R01 CA089440NCI NIH HHS R01 CA140602NIAID NIH HHS U19 AI057234PHS HHS U19 AIO57234
6 · The paper itself

Abstract

Owing to their properties, dendritic cells (DCs) are often called 'nature's adjuvants' and thus have become the natural targets for antigen delivery. DCs provide an essential link between the innate and the adaptive immune responses. DCs are at the center of the immune system owing to their ability to control both tolerance and immunity. DCs are thus key targets for both preventive and therapeutic vaccination. Herein, we will discuss recent progresses in our understanding of DC subsets physiology as it applies to vaccination.

Indexed as

VaccinationAnimalsCell- and Tissue-Based TherapyDendritic CellsHumansImmunity, CellularImmunity, Humoral

Identifiers

PMID23725656
PMCPMC3711217

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.