ArticleISRN microbiology2011
Toxins and Antibiotic Resistance in Staphylococcus aureus Isolated from a Major Hospital in Lebanon.
Article in ISRN microbiology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed.
- High prevalence and multidrug resistance of Methicillin-resistant Staphylococcus aureus at a provincial referral hospital in Zambia: A 5-year retrospective study.PLOS global public health · 2026Article
- Methicillin-ResistantAntibiotics (Basel, Switzerland) · 2022Article
- Prevalence of methicillin-resistant Staphylococcus aureus in Iranian children: a systematic review and meta-analysis.Clinical and experimental pediatrics · 2021Article
- Surveillance of antimicrobial resistance in low- and middle-income countries: a scattered picture.Antimicrobial resistance and infection control · 2021Review
- Phenotypic and Genotypic Characterization with MALDI-TOF-MS Based Identification ofInternational journal of environmental research and public health · 2020Article
- Prevalence ofAccess microbiology · 2019Article
- Distribution of tsst-1 and mecA Genes in Staphylococcus aureus Isolated From Clinical Specimens.Jundishapur journal of microbiology · 2016Article
- Methicillin-Resistant Staphylococcus aureus Isolated From Various Types of Hospital Infections in Pediatrics: Panton-Valentine Leukocidin, Staphylococcal Chromosomal Cassette mec SCCmec Phenotypes and Antibiotic Resistance Properties.Jundishapur journal of microbiology · 2015Article
- Resistant Strains of Enterotoxigenic Staphylococcus aureus; Unknown Risk for Multiple Sclerosis Exacerbation.Iranian Red Crescent medical journal · 2015Article
- Meticillin-resistant Staphylococcus aureus isolated from Iranian hospitals: virulence factors and antibiotic resistance properties.Bosnian journal of basic medical sciences · 2014Article
- Occurrence of Methicillin Resistant and Enterotoxigenic Staphylococcus aureus in Traditional Cheeses in the North West of Iran.ISRN microbiology · 2014Article
- High incidence of oxacillin-susceptible mecA-positive Staphylococcus aureus (OS-MRSA) associated with bovine mastitis in China.PloS one · 2014Article
- Genome analysis of Staphylococcus aureus ST291, a double locus variant of ST398, reveals a distinct genetic lineage.PloS one · 2013Article
Corrections and comments
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Authors and funding
5 authors.
Funding
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Abstract
Molecular characterization of Staphylococcus aureus is of both clinical and infection control importance. Virulence determinants using PCR and multiple drug resistance profiles were studied in 130 S. aureus isolates. PCR-RFLP analysis of the 16S-23S DNA spacer region was done to investigate the level of 16S-23S ITS (internal transcribed spacer) polymorphism. Methicillin-resistant S. aureus (MRSA), which represented 72% of the studied isolates, showed multiple drug resistance with 18% being resistant to 10-18 of the drugs used compared to a maximum resistance to 9 antibiotics with the methicillin sensitive S. aureus (MSSA) isolates. Exfoliative toxin A (ETA) was more prevalent than B (ETB) with virulent determinants being additionally detected in multiple drug-resistant isolates. 16S-23S ITS PCR-RFLP combined with sequencing of the primary product was successful in generating molecular fingerprints of S. aureus and could be used for preliminary typing. This is the first study to demonstrate the incidence of virulent genes, ACME, and genetic diversity of S. aureus isolates in Lebanon. The data presented here epitomize a starting point defining the major genetic populations of both MRSA and MSSA in Lebanon and provide a basis for clinical epidemiological studies.
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Registered trials
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