ArticlePloS one2013
Forced expiratory volume in one second predicts length of stay and in-hospital mortality in patients undergoing cardiac surgery: a retrospective cohort study.
Article in PloS one, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
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Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it, 47 citations in OpenAlex.
- Pulmonary Function Tests for the Prediction of Postoperative Pulmonary Complications.Deutsches Arzteblatt international · 2022Pooled it
- Trial
- Pulmonary function test parameters before liver transplantation predict post-transplant survival and respiratory-related death.Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society · 2026Article
- Value-Based Pricing of Health Services With Health Equity Considerations.Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research · 2026Article
- Pulmonary Risk Stratification in Open Thoracoabdominal Aortic Aneurysm Repair.Journal of clinical medicine · 2026Article
- Lung scRNA-seq reveals chronic inflammation and emphysemous phenotype in mice with osteogenesis imperfecta.Frontiers in genetics · 2026Article
- Navigating data availability challenges in healthcare: assessing the added value of pulmonary function testing to the Care Assessment Need score for mortality risk.BMJ health & care informatics · 2025Article
- Preoperative pulmonary function is associated with left ventricular assist device outcomes.Surgery in practice and science · 2024Article
- Liposomal bupivacaine intercostal block placed under direct vision reduces morphine use in thoracic surgery.Journal of thoracic disease · 2024Article
- Association between hospital-acquired functional decline and 2-year readmission or mortality after cardiac surgery in older patients: a multicenter, prospective cohort study.Aging clinical and experimental research · 2023Article
- Hospital-Acquired Functional Decline and Clinical Outcomes in Older Cardiac Surgical Patients: A Multicenter Prospective Cohort Study.Journal of clinical medicine · 2022Article
- Spirometry Assessment and Correlation With Postoperative Pulmonary Complications in Cardiac Surgery Patients.Cureus · 2020Article
- Postoperative Delirium in Patients with Chronic Obstructive Pulmonary Disease after Coronary Artery Bypass Grafting.Medicina (Kaunas, Lithuania) · 2020Article
- Association of preoperative spirometry with cardiopulmonary fitness and postoperative outcomes in surgical patients:EClinicalMedicine · 2020Article
- A multicenter study to evaluate pulmonary function in osteogenesis imperfecta.Clinical genetics · 2018Article
- The Efficacy of Inpatient vs. Home-Based Physiotherapy Following Coronary Artery Bypass Grafting.International journal of environmental research and public health · 2018Observational
- The Relationship between Diabetes Mellitus and Respiratory Function in Patients Eligible for Coronary Artery Bypass Grafting.International journal of environmental research and public health · 2018Article
- Analysis of the influence of respiratory disorders observed in preoperative spirometry on the dynamics of early inflammatory response in patients undergoing isolated coronary artery bypass grafting.Clinical interventions in aging · 2017Article
- A study on the outcome of preoperative pulmonary function tests on a patient undergoing rheumatic mitral valve surgery.Journal of anaesthesiology, clinical pharmacologyArticle
Corrections and comments
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Authors and funding
9 authors at 4 institutions in 1 country.
Funding
Abstract
objectiveAn aging population and increasing use of percutaneous therapies have resulted in older patients with more co-morbidity being referred for cardiac surgery. Objective measurements of physiological reserve and severity of co-morbid disease are required to improve risk stratification. We hypothesised that FEV1 would predict mortality and length of stay following cardiac surgery.
methodsWe assessed clinical outcomes in 2,241 consecutive patients undergoing coronary artery bypass grafting and/or valve surgery from 2001 to 2007 in a regional cardiac centre. Generalized linear models of the association between FEV1 and length of hospital stay and mortality were adjusted for age, sex, height, body mass index, socioeconomic status, smoking, cardiovascular risk factors, long-term use of bronchodilators or steroids for lung disease, and type and urgency of surgery. FEV1 was compared to an established risk prediction model, the EuroSCORE.
resultsSpirometry was performed in 2,082 patients (93%) whose mean (SD) age was 67 (10) years. Median hospital stay was 3 days longer in patients in the lowest compared to the highest quintile for FEV1, 1.35-fold higher (95% CI 1.20-1.52; p<0.001). The adjusted odds ratio for mortality was increased 2.11-fold (95% CI 1.45-3.08; p<0.001) per standard deviation decrement in FEV1 (800 ml). FEV1 improved discrimination of the EuroSCORE for mortality. Similar associations were found after excluding people with known pulmonary disease and/or airflow limitation on spirometry.
conclusionsReduced FEV1 strongly predicted increased length of stay and in-hospital mortality following cardiac surgery. FEV1 is a widely available measure of physiological health that may improve risk stratification of complex patients undergoing cardiac surgery and should be evaluated for inclusion in new prediction tools.
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