Evidence map›Paper›PMID 23722972›Full record

ReviewJournal of magnetic resonance imaging : JMRI2013

Biomedical applications of sodium MRI in vivo.

Guillaume Madelin, Ravinder R Regatte

Open access · bronzeAbstract readReview
In one paragraph

Review in Journal of magnetic resonance imaging : JMRI, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 122 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
122citing papers in PubMed, 1 pooled it
14.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

122 citing papers in PubMed, 1 synthesis or guideline pooled it, 248 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Trial
  4. Trial
  5. Trial
  6. Triple-PulseMagnetic resonance in medicine · 2026
    Article
  7. A Sub-Microsecond Switch Enabling SWIFTMagnetic resonance in medicine · 2026
    Article
  8. Article
  9. Article
  10. Estimation of skin sodium content viaMagma (New York, N.Y.) · 2026
    Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Review
  18. Observational
  19. Article
  20. Article

62 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Guillaume MadelinNew York University Langone Medical Center, Department of Radiology, Center for Biomedical Imaging, New York, NY 10016, USA. guillaume.madelin@nyumc.org
Ravinder R Regatte
NYU Langone Health · US

Funding

PSYCHOSOCIAL COREP30AG008051 · NIA · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI SHAO, YONGZHAO · 1990 to 2019
$36.1M
Sodium MRI for Assessment of Early OA.R01AR060238 · NIAMS · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI REGATTE, RAVINDER · 2011 to 2015
$2.9M
Cartilage, Bone and Marrow Interactions in Knee OAR01AR056260 · NIAMS · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI REGATTE, RAVINDER · 2010 to 2014
$2.5M
Quantitative MRI for Early Diagnosis of ArthritisR01AR053133 · NIAMS · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI REGATTE, RAVINDER · 2007 to 2011
$1.8M
NIAMS NIH HHS R01 AR053133NIAMS NIH HHS R01 AR056260NIAMS NIH HHS R01 AR060238NIA NIH HHS P30 AG008051
6 · The paper itself

Abstract

In this article we present an up-to-date overview of the potential biomedical applications of sodium magnetic resonance imaging (MRI) in vivo. Sodium MRI is a subject of increasing interest in translational imaging research as it can give some direct and quantitative biochemical information on the tissue viability, cell integrity and function, and therefore not only help the diagnosis but also the prognosis of diseases and treatment outcomes. It has already been applied in vivo in most human tissues, such as brain for stroke or tumor detection and therapeutic response, in breast cancer, in articular cartilage, in muscle, and in kidney, and it was shown in some studies that it could provide very useful new information not available through standard proton MRI. However, this technique is still very challenging due to the low detectable sodium signal in biological tissue with MRI and hardware/software limitations of the clinical scanners. The article is divided in three parts: 1) the role of sodium in biological tissues, 2) a short review on sodium magnetic resonance, and 3) a review of some studies on sodium MRI on different organs/diseases to date.

Indexed as

SodiumContrast MediaHumansImage EnhancementMagnetic Resonance ImagingContrast MediaSodiumbiochemicalmagnetic resonance imagingquadrupolarsodium

Identifiers

PMID23722972
PMCPMC3759542
OpenAlexW1827197946

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.