Evidence map›Paper›PMID 23722731›Full record

ArticleMolecules (Basel, Switzerland)2013

Design, synthesis and evaluation of dual-modality glyco-nanoparticles for tumor imaging.

Hua Zhu, Jun Zhao, Xinfeng Lin, Ye Hong, Chun Li, Zhi Yang

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Article
  3. Nanoparticles and radiotracers: advances toward radionanomedicine.Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology · 2016
    Review
  4. Article
  5. Article
  6. Review
  7. Nanoparticles for multimodal in vivo imaging in nanomedicine.International journal of nanomedicine · 2014
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Hua ZhuKey Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Department of Nuclear Medicine, Peking University Cancer Hospital & Institute, Beijing 100142, China.
Jun Zhao
Xinfeng Lin
Ye Hong
Chun Li
Zhi Yang

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

d-Glucosamine (DG) was conjugated to a core-cross linked polymeric micelle (CCPM) system equipped with both a near-infrared fluorophore (NIRF) and a gamma emitter (111In). The resultant nano-scale tumor-targeting imaging tracer, 111In-DG-NIRF-CCPM, selectively accumulated in a human epithelial carcinoma A-431 xenograft model in mice. At 24 hrs post injection, the tumor uptake was 2.62 ± 0.80 % of the injected dose per gram of tissue (%ID/g). Tumors were clearly delineated in both single-photon emission computed tomography (SPECT) and optical imaging. The results suggest that the prepared imaging tracer is a promising agent for tumor diagnosis.

Indexed as

Tomography, Emission-Computed, Single-PhotonAnimalsCell Line, TumorGlucosamineHeterograftsHumansIsotope LabelingMiceNanoparticlesNeoplasmsRadiopharmaceuticalsTissue DistributionGlucosamineRadiopharmaceuticals

Identifiers

PMID23722731
PMCPMC6269689

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.