Evidence map›Paper›PMID 23722610›Full record

ArticleJournal of acquired immune deficiency syndromes (1999)2013

Evaluating sleep and cognition in HIV.

Charlene E Gamaldo, Alyssa Gamaldo, Jason Creighton, Rachel E Salas, Ola A Selnes, Paula M David, Gilbert Mbeo, Benjamin S Parker, Amanda Brown, Justin C McArthur and 1 more

2 registry-linked trialsAbstract read
In one paragraph

Article in Journal of acquired immune deficiency syndromes (1999), 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 34 papers.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02571595 naterminatednot on this mapstarted 2015, after this paper: background citation

Efficacy Potential of an Internet-based Sleep Program to Improve Sleep Quality in People With HIV

TypeinterventionalSponsorMcGill UniversityRan2015 to 2020Enrolled27ConditionsHIV - Human Immunodeficiency Virus, Insomnia DisorderArmsDigital cognitive behavioural therapy for insomnia (dCBT-I)
NCT05155787 nacompletednot on this mapstarted 2021, after this paper: background citation

Construction and Evaluation of Neurofeedback Training (NFT) on Sleep Quality and Cognitive Function Performance Among HIV-infected Persons

TypeinterventionalSponsorNational Cheng-Kung University HospitalRan2021 to 2023Enrolled13ConditionsPoor Quality Sleep, HIV InfectionsArmsNeurofeedback, Shame neurofeedback
3 · Its place in the literature

Who cites it

34 citing papers in PubMed.

  1. Trial
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  5. Review
  6. Review
  7. Article
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  11. Article
  12. Article
  13. Sleep, Prospective Memory, and Immune Status among People Living with HIV.International journal of environmental research and public health · 2021
    Article
  14. Article
  15. Behavioral and Physical Activity Interventions for HAND.Current topics in behavioral neurosciences · 2021
    Review
  16. Personality Traits and the Subjective and Objective Experience of Sleep.International journal of behavioral medicine · 2020
    Article
  17. Identifying Sleep Biomarkers to Evaluate Cognition in HIV.Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference · 2020
    Article
  18. Cognitive Trajectory Phenotypes in Human Immunodeficiency Virus-Infected Patients.Journal of acquired immune deficiency syndromes (1999) · 2019
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors.

Charlene E Gamaldo*Department of Neurology, Johns Hopkins University, Baltimore, MD; †Laboratory of Behavioral Neuroscience, National Institute on Aging, Baltimore, MD; ‡Departments of Pathology, Epidemiology, and Medicine, Johns Hopkins University, Baltimore, MD; and §Department of Psychiatry and Behavioral Medicine, Johns Hopkins University, Baltimore, MD.
Alyssa Gamaldo
Jason Creighton
Rachel E Salas
Ola A Selnes
Paula M David
Gilbert Mbeo
Benjamin S Parker
Amanda Brown
Justin C McArthur
Michael T Smith

Funding

Institute for Clinical and Translational Research (UL1)UL1RR025005 · NCRR · JOHNS HOPKINS UNIVERSITY · PI FORD, DANIEL ERNEST · 2007 to 2011
$75.8M
Therapeutic CoreP30MH075673 · NIMH · JOHNS HOPKINS UNIVERSITY · PI Leah Helane Rubin · 2006 to 2026
$33.2M
Sleep Disturbance, Central Pain Modulation, and Clinical Pain in OsteoarthritisR01AR054871 · NIAMS · JOHNS HOPKINS UNIVERSITY · PI SMITH, MICHAEL T · 2007 to 2011
$3.1M
Translational Research in Neuro-AIDS and Mental HealthR25MH080661 · NIMH · JOHNS HOPKINS UNIVERSITY · PI MCARTHUR, JUSTIN CHARLES. · 2007 to 2019
$2.9M
NCRR NIH HHS UL1 RR 025005NCRR NIH HHS UL1 RR025005NIAMS NIH HHS R01 AR054871NIMH NIH HHS 5P30MH075673-S02NIMH NIH HHS P30 MH075673NIMH NIH HHS R25 MH080661
6 · The paper itself

Abstract

objectiveTo examine the relationship between measures of sleep quality and cognitive performance in HIV-positive individuals stable on combination antiretroviral therapy.

designMultimethod assessments of sleep quality, patterns, and cognitive performance were assessed in a predominantly black HIV-positive cohort.

methodsSleep quality and patterns were characterized in 36 subjects by polysomnogram, 2-week actigraphy monitoring, and validated sleep questionnaires. Cognitive performance was assessed with a battery of neuropsychological tests.

resultsThe majority of participants were cognitively impaired [based on Frascati (75%) criteria]. Self-reported mean scores on the Pittsburgh sleep quality index and the insomnia severity scale suggested poor sleep quality. Better cognitive performance, particularly on tasks of attention, frontal/executive function, and psychomotor/motor speed, was associated with polysomnogram sleep indices (ie, reduced wake after sleep onset, greater sleep efficiency, greater sleep latency, and greater total sleep time). Thirty-seven percent of participants had sleep patterns suggestive of chronic partial sleep deprivation, which was associated with significantly worse performance on the digit symbol test (P = 0.006), nondominant pegboard (P = 0.043), and verbal fluency tests (P = 0.044).

conclusionsOur results suggest that compromised sleep quality and duration may have a significant impact on cognitive performance in HIV-positive individuals. Future studies are warranted to determine the utility of sleep quality and quantity indices as potential predictive biomarkers for development and progression of future HIV-associated neurocognitive disorder.

Indexed as

AdultAnti-Retroviral AgentsCognition DisordersFemaleHIV InfectionsHumansMaleMiddle AgedNeuropsychological TestsPolysomnographyPrevalenceSleep Wake DisordersAnti-Retroviral Agents

Identifiers

PMID23722610
PMCPMC3822901

What OpenQuestion holds

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Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.