Evidence map›Paper›PMID 23722009›Full record

ArticleInternational journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience2013

Mapping connectivity in the developing brain.

Emily L Dennis, Paul M Thompson

Open access · greenAbstract read
In one paragraph

Article in International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed, 1 pooled it
6.5field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 1 synthesis or guideline pooled it, 79 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Cortically constrained shape recognition: Automated white matter tract segmentation validated in the pediatric brain.Journal of neuroimaging : official journal of the American Society of Neuroimaging · 2021
    Article
  6. Review
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Functional Connectivity of the Human Brain in Utero.Trends in cognitive sciences · 2016
    Review
  17. Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Emily L DennisImaging Genetics Center, Laboratory of Neuro Imaging, UCLA School of Medicine, 635 Charles Young Drive South, Suite 225, Los Angeles, CA 90095-7334, USA. Electronic address: eldennis@ucla.edu.
Paul M Thompson
UCLA Health · US

Funding

Autism Genetics, Phase II: Increasing Representation of Human DiversityR01MH100027 · NIMH · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI GESCHWIND, DANIEL H · 2013 to 2024
$31.7M
YALE CENTER FOR THE: LEARNING &ATTENTIONP41RR013642 · NCRR · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI BEARER, ELAINE L · 1998 to 2011
$21.9M
A Comprehensive Approach to Identification of Autism Susceptibility GenesR01MH081754 · NIMH · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI GESCHWIND, DANIEL H · 2008 to 2012
$14.6M
HARDI Mapping of Disease Effects on the BrainR01EB008432 · NIBIB · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI THOMPSON, PAUL M · 2009 to 2012
$2.6M
Genetic influences on the brain: A twin imaging studyR01HD050735 · NICHD · QUEENSLAND INSTITUTE OF MEDICAL RESEARCH · PI WRIGHT, MARGARET JANE · 2007 to 2011
$2.6M
Training Grant in Neurobehavioral GeneticsT32MH073526 · NIMH · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI BEARDEN, CARRIE E, GESCHWIND, DANIEL H · 2006 to 2020
$2.4M
A Multidimensional Alzheimer's Disease Brain AtlasR01EB008281 · NIBIB · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI THOMPSON, PAUL M · 2007 to 2010
$1.4M
Computational Modeling of High-Field MR ImagesR01EB007813 · NIBIB · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI THOMPSON, PAUL M · 2007 to 2010
$1.3M
NCRR NIH HHS P41 RR013642NIBIB NIH HHS EB007813NIBIB NIH HHS EB008281NIBIB NIH HHS EB008432NIBIB NIH HHS R01 EB007813NIBIB NIH HHS R01 EB008281NIBIB NIH HHS R01 EB008432NICHD NIH HHS R01 HD050735NIMH NIH HHS R01 MH081754NIMH NIH HHS R01 MH100027NIMH NIH HHS T32 MH073526NIMH NIH HHS T32MH073526-06
6 · The paper itself

Abstract

Recently, there has been a wealth of research into structural and functional brain connectivity, and how they change over development. While we are far from a complete understanding, these studies have yielded important insights into human brain development. There is an ever growing variety of methods for assessing connectivity, each with its own advantages. Here we review research on the development of structural and/or functional brain connectivity in both typically developing subjects and subjects with neurodevelopmental disorders. Space limitations preclude an exhaustive review of brain connectivity across all developmental disorders, so we review a representative selection of recent findings on brain connectivity in autism, Fragile X, 22q11.2 deletion syndrome, Williams syndrome, Turner syndrome, and ADHD. Major strides have been made in understanding the developmental trajectory of the human connectome, offering insight into characteristic features of brain development and biological processes involved in developmental brain disorders. We also discuss some common themes, including hemispheric specialization - or asymmetry - and sex differences. We conclude by discussing some promising future directions in connectomics, including the merger of imaging and genetics, and a deeper investigation of the relationships between structural and functional connectivity.

Indexed as

Brain MappingBrainDevelopmental DisabilitiesHumansNeural Pathways22q11.2 DSADHDAutismBrain connectivityDevelopmentDTIFragile XHARDIrs-fMRITurner syndromeWilliams syndrome

Identifiers

PMID23722009
PMCPMC3800504
OpenAlexW2088886113

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.