Evidence map›Paper›PMID 23721984›Full record

Trial reportContemporary clinical trials2013

Lifestyle Modification in Blood Pressure Study II (LIMBS): study protocol of a randomized controlled trial assessing the efficacy of a 24 week structured yoga program versus lifestyle modification on blood pressure reduction.

Debbie L Cohen, Anne Bowler, Stephen A Fisher, Angela Norris, Andrew Newberg, Hengyi Rao, Rupal Bhavsar, John A Detre, Thomas Tenhave, Raymond R Townsend

Abstract readClinical Trial, Phase IIRandomized Controlled Trial
In one paragraph

Trial report in Contemporary clinical trials, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Trial
  4. Article
  5. Yoga and Hypertension.Journal of yoga & physical therapy · 2013
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Debbie L CohenPerelman School of Medicine at the University of Pennsylvania, Department of Medicine, Renal, Electrolyte and Hypertension Division, Philadelphia, PA 190104, USA. debbie.cohen@uphs.upenn.edu
Anne Bowler
Stephen A Fisher
Angela Norris
Andrew Newberg
Hengyi Rao
Rupal Bhavsar
John A Detre
Thomas Tenhave
Raymond R Townsend

Funding

Lifestyle Modification and blood Pressure Study (LIMBS)R01AT004921 · NCCIH · UNIVERSITY OF PENNSYLVANIA · PI COHEN, DEBBIE L · 2009 to 2013
$1.7M
NCCIH NIH HHS 1R01AT004921-01A1NCCIH NIH HHS R01 AT004921
6 · The paper itself

Abstract

Hypertension is a major public health issue affecting 68 million adults in the United States. Lifestyle modifications including complementary therapies such as the movement based mind body practice of yoga have become increasingly popular in the United States and have been considered as a potential alternative to medication in blood pressure reduction. We completed a pilot study in 2009 which showed meaningful decreases in 24-hour ambulatory blood pressure readings after a 12 week period of yoga participation. Based on data from our pilot study we are now completing The Lifestyle Modification and Blood Pressure Study (LIMBS II) which is a phase 2 randomized controlled trial designed to determine the effects of yoga therapy and enhanced lifestyle modification on lowering blood pressure in pre-hypertensive and stage 1 hypertensive subjects. Using 24-hour ambulatory blood pressure monitoring, LIMBS II aims to compare the effects on blood pressure reduction in subjects randomized for 24 weeks to one of the three following groups: yoga therapy versus blood pressure education program (sodium restriction and walking program) versus a combination program that involves components of both groups. LIMBS II will also examine the impact that changes in blood pressure have on cerebral blood flow. If successful, the LIMBS study will determine if yoga therapy combined with enhanced lifestyle modification will result in clinically meaningful decreases in blood pressure and thus can be implemented as an alternative to drug therapy for patients with prehypertension and stage 1 hypertension.

Indexed as

Blood PressureLife StyleResearch DesignYogaAdolescentAdultAgedBlood Chemical AnalysisBody Mass IndexFemaleHealth BehaviorHumansHypertensionMaleMiddle AgedUrinalysisFunctional MRIHypertensionPhase 2 clinical randomized trialPrehypertensionYoga

Identifiers

PMID23721984
PMCPMC4593488

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.