Trial reportThe Journal of clinical endocrinology and metabolism2013
PTSD symptom reduction with mindfulness-based stretching and deep breathing exercise: randomized controlled clinical trial of efficacy.
Trial report in The Journal of clinical endocrinology and metabolism, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 42 papers, 11 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The Efficacy of Mindfulness-Based Stretching and Breathing Exercise as a Complementary Therapy for Posttraumatic Stress Disorder: A Prospective Randomized Study
Development and Evaluation of an Online Mental Health Program for Traumatized Female College Students: A Randomized Controlled Trial
An Emoji-based Attention Bias Modification Intervention for Depressive Symptom Severity in Young Adults
Who cites it
42 citing papers in PubMed, 11 syntheses or guidelines pooled it, 130 citations in OpenAlex.
- Effectiveness of Meditation Techniques in Treating Post-Traumatic Stress Disorder: A Systematic Review and Meta-Analysis.Medicina (Kaunas, Lithuania) · 2024Pooled it
- Only Small Effects of Mindfulness-Based Interventions on Biomarker Levels of Inflammation and Stress: A Preregistered Systematic Review and Two Three-Level Meta-Analyses.International journal of molecular sciences · 2023Pooled it
- Is exercise/physical activity effective at reducing symptoms of post-traumatic stress disorder in adults - A systematic review.Frontiers in psychology · 2022Pooled it
- Psychological Interventions for Healthcare Providers With PTSD in Life-Threatening Pandemic: Systematic Review and Meta-Analysis.Frontiers in psychiatry · 2021Pooled it
- Mind-Body Exercises for PTSD Symptoms, Depression, and Anxiety in Patients With PTSD: A Systematic Review and Meta-Analysis.Frontiers in psychology · 2021Pooled it
- Effects of Mindfulness-Based Interventions on Biomarkers and Low-Grade Inflammation in Patients with Psychiatric Disorders: A Meta-Analytic Review.International journal of molecular sciences · 2020Pooled it
- Body- and Movement-Oriented Interventions for Posttraumatic Stress Disorder: A Systematic Review and Meta-Analysis.Journal of traumatic stress · 2019Pooled it
- A systematic review of randomized trials of mind-body interventions for PTSD.Journal of clinical psychology · 2018Pooled it
- Yoga for posttraumatic stress disorder - a systematic review and meta-analysis.BMC psychiatry · 2018Pooled it
- Meditation and yoga for posttraumatic stress disorder: A meta-analytic review of randomized controlled trials.Clinical psychology review · 2017Pooled it
- Exercise as Treatment for Anxiety: Systematic Review and Analysis.Annals of behavioral medicine : a publication of the Society of Behavioral Medicine · 2015Pooled it
- Trial
- Group integrated exercise versus recovery class for veterans with posttraumatic stress disorder: a randomized clinical trial.BMC psychiatry · 2025Trial
- Momentary effects of life stressors on mindfulness and emotion regulation difficulties among adolescents exposed to chronic stressors.Stress and health : journal of the International Society for the Investigation of Stress · 2024Trial
- Effect of Mindfulness-Based Stress Reduction on dehydroepiandrosterone-sulfate in adults with self-reported stress. A randomized trial.Clinical and translational science · 2021Trial
- Trial
- Efficacy of mindfulness-based addiction treatment (MBAT) for smoking cessation and lapse recovery: A randomized clinical trial.Journal of consulting and clinical psychology · 2016Trial
- Exercise Interventions for PTSD: A Systematic Review and Network Meta-Analysis of Overall Effects, Comparative Effectiveness, and Ranking Uncertainty.Healthcare (Basel, Switzerland) · 2026Review
- Positive Effects of Conscious Connected Breathing Exercises on Sexual Function, Sleep, and Mood in Women with Fibromyalgia Syndrome Compared to Controls.Mediterranean journal of rheumatology · 2026Article
- Mindfulness-based controlled breathing and the effect on performing a transnasal endoscopy: a quasi-experimental study.Frontiers in medicine · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 3 institutions in 1 country.
Funding
Abstract
contextAbnormal cortisol levels are a key pathophysiological indicator of post-traumatic stress disorder (PTSD). Endogenous normalization of cortisol concentration through exercise may be associated with PTSD symptom reduction.
objectiveThe aim of the study was to determine whether mindfulness-based stretching and deep breathing exercise (MBX) normalizes cortisol levels and reduces PTSD symptom severity among individuals with subclinical features of PTSD. DESIGN AND
settingA randomized controlled trial was conducted at the University of New Mexico Health Sciences Center.
participantsTwenty-nine nurses (28 female) aged 45-66 years participated in the study.
interventionSixty-minute MBX sessions were conducted semiweekly for 8 weeks.
main outcome measuresSerum cortisol was measured, and the PTSD Checklist-Civilian version (PCL-C) was performed at baseline and weeks 4, 8, and 16.
resultsTwenty-nine participants completed the study procedures, 22 (79%) with PTSD symptoms (MBX, n = 11; control, n = 11), and 7 (21%) without PTSD (BASE group). Eight-week outcomes for the MBX group were superior to those for the control group (mean difference for PCL-C scores, -13.6; 95% confidence interval [CI], -25.6, -1.6; P = .01; mean difference for serum cortisol, 5.8; 95% CI, 0.83, 10.8; P = .01). No significant differences were identified between groups in any other items. The changes in the MBX group were maintained at the 16-week follow-up (P = .85 for PCL-C; P = .21 for cortisol). Our data show that improved PTSD scores were associated with normalization of cortisol levels (P < .05).
conclusionsThe results suggest that MBX appears to reduce the prevalence of PTSD-like symptoms in individuals exhibiting subclinical features of PTSD.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.