Evidence map›Paper›PMID 23720759›Full record

ReviewThe Journal of biological chemistry2013

mRNA on the move: the road to its biological destiny.

Carolina Eliscovich, Adina R Buxbaum, Zachary B Katz, Robert H Singer

Abstract readReview
In one paragraph

Review in The Journal of biological chemistry, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Review
  6. In Vivo Visualization of Mobile mRNA Particles in Plants Using BglG.Methods in molecular biology (Clifton, N.J.) · 2022
    Article
  7. Article
  8. The Great Escape: mRNA Export through the Nuclear Pore Complex.International journal of molecular sciences · 2021
    Review
  9. Article
  10. Review
  11. Review
  12. Review
  13. Review
  14. Article
  15. Review
  16. β-Actin mRNA interactome mapping by proximity biotinylation.Proceedings of the National Academy of Sciences of the United States of America · 2019
    Article
  17. Article
  18. Zipcode Binding Protein 1 (ZBP1; IGF2BP1): A Model for Sequence-Specific RNA Regulation.Cold Spring Harbor symposia on quantitative biology · 2019
    Article
  19. A newRNA (New York, N.Y.) · 2017
    Article
  20. RNP transport in cell biology: the long and winding road.Current opinion in cell biology · 2017
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Carolina EliscovichDepartment of Anatomy and Structural Biology, Albert Einstein College of Medicine of Yeshiva University, Bronx, New York 10461, USA.
Adina R Buxbaum
Zachary B Katz
Robert H Singer

Funding

TRAINING PROGRAM IN CELLULAR &MOLEC. BIOLOGY &GENETICST32GM007491 · NIGMS · YESHIVA UNIVERSITY · PI QUERY, CHARLES C · 1985 to 2021
$17.0M
RNA TRANSPORT AND LOCALIZATION IN YEAST IN SITUR01GM057071 · NIGMS · YESHIVA UNIVERSITY · PI SINGER, ROBERT H · 1998 to 2019
$5.7M
LIGHT-ACTIVATED GENE EXPRESSION IN SINGLE CELLS WITHIN TISSUER01GM086217 · NIGMS · ALBERT EINSTEIN COLLEGE OF MEDICINE · PI SINGER, ROBERT H · 2008 to 2011
$2.9M
Mechanism of Actin mRNA LocalizationR01GM084364 · NIGMS · ALBERT EINSTEIN COLLEGE OF MEDICINE · PI SINGER, ROBERT H · 2008 to 2012
$1.9M
NIGMS NIH HHS GM57071NIGMS NIH HHS GM84364NIGMS NIH HHS R01 GM057071NIGMS NIH HHS R01 GM084364NIGMS NIH HHS R01 GM086217NIGMS NIH HHS T32 GM007491
6 · The paper itself

Abstract

Cells have evolved to regulate the asymmetric distribution of specific mRNA targets to institute spatial and temporal control over gene expression. Over the last few decades, evidence has mounted as to the importance of localization elements in the mRNA sequence and their respective RNA-binding proteins. Live imaging methodologies have shown mechanistic details of this phenomenon. In this minireview, we focus on the advanced biochemical and cell imaging techniques used to tweeze out the finer aspects of mechanisms of mRNA movement.

Indexed as

AnimalsCytoplasmHumansIn Situ HybridizationMicroscopy, FluorescenceModels, GeneticRNA-Binding ProteinsRNA, MessengerRNA PrecursorsRNA TransportRNA-Binding ProteinsRNA, MessengerRNA Precursors3′-UTRFluorescenceGene ExpressionIn Vivo ImagingLocalization Element/ZipcodemRNARNA-binding ProteinsRNA-Protein InteractionRNA Transportβ-Actin mRNA

Identifiers

PMID23720759
PMCPMC3711302

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.