ArticleJournal of virology2013
Genome-wide characterization of endogenous retroviruses in the bat Myotis lucifugus reveals recent and diverse infections.
Article in Journal of virology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
24 citing papers in PubMed, 45 citations in OpenAlex.
- An ancient alpharetrovirus lineage in bats: Evolutionary insights and possible roles in reproduction.PLoS genetics · 2026Article
- Signature of viral fossils: a comparative genomics approach to understand the diversity of endogenous retroviruses in bats.Virus research · 2024Article
- Chiropterans Are a Hotspot for Horizontal Transfer of DNA Transposons in Mammalia.Molecular biology and evolution · 2023Article
- Article
- Analyzing the Evolution and Host Adaptation of the Rabies Virus from the Perspective of Codon Usage Bias.Transboundary and emerging diseases · 2023Article
- Genome-Wide Characterization of Zebrafish Endogenous Retroviruses Reveals Unexpected Diversity in Genetic Organizations and Functional Potentials.Microbiology spectrum · 2021Article
- Recombination Marks the Evolutionary Dynamics of a Recently Endogenized Retrovirus.Molecular biology and evolution · 2021Article
- Article
- Functions and Regulation of Endogenous Retrovirus Elements during Zygotic Genome Activation: Implications for Improving Somatic Cell Nuclear Transfer Efficiency.Biomolecules · 2021Review
- Origin and recent expansion of an endogenous gammaretroviral lineage in domestic and wild canids.Retrovirology · 2019Article
- Complete Endogenous Retrovirus Genome Sequence from a Brazilian Vampire Bat (Desmodus rotundus).Microbiology resource announcements · 2019Article
- Article
- Horizontal acquisition of transposable elements and viral sequences: patterns and consequences.Current opinion in genetics & development · 2018Review
- Genome-Wide Characterization of Endogenous Retroviruses inFrontiers in microbiology · 2018Article
- Article
- Co-option of endogenous viral sequences for host cell function.Current opinion in virology · 2017Review
- Bats and Rodents Shape Mammalian Retroviral Phylogeny.Scientific reports · 2015Article
- A novel endogenous betaretrovirus in the common vampire bat (Desmodus rotundus) suggests multiple independent infection and cross-species transmission events.Journal of virology · 2015Article
- Comparative paleovirological analysis of crustaceans identifies multiple widespread viral groups.Mobile DNA · 2015Article
- Cross-Species Transmission and Differential Fate of an Endogenous Retrovirus in Three Mammal Lineages.PLoS pathogens · 2015Article
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
Abstract
Bats are increasingly recognized as reservoir species for a variety of zoonotic viruses that pose severe threats to human health. While many RNA viruses have been identified in bats, little is known about bat retroviruses. Endogenous retroviruses (ERVs) represent genomic fossils of past retroviral infections and, thus, can inform us on the diversity and history of retroviruses that have infected a species lineage. Here, we took advantage of the availability of a high-quality genome assembly for the little brown bat, Myotis lucifugus, to systematically identify and analyze ERVs in this species. We mined an initial set of 362 potentially complete proviruses from the three main classes of ERVs, which were further resolved into 13 major families and 86 subfamilies by phylogenetic analysis. Consensus or representative sequences for each of the 86 subfamilies were then merged to the Repbase collection of known ERV/long terminal repeat (LTR) elements to annotate the retroviral complement of the bat genome. The results show that nearly 5% of the genome assembly is occupied by ERV-derived sequences, a quantity comparable to findings for other eutherian mammals. About one-fourth of these sequences belong to subfamilies newly identified in this study. Using two independent methods, intraelement LTR divergence and analysis of orthologous loci in two other bat species, we found that the vast majority of the potentially complete proviruses identified in M. lucifugus were integrated in the last ~25 million years. All three major ERV classes include recently integrated proviruses, suggesting that a wide diversity of retroviruses is still circulating in Myotis bats.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.