ArticleFrontiers in neurology2013
Twenty-four hour non-invasive ambulatory blood pressure and heart rate monitoring in Parkinson's disease.
Article in Frontiers in neurology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04251728 (Chronic Effects of Automated Mechanical Peripheral Stimulation on Cardiovascular and Functional Variables in Patients With Parkinson's Disease), which is not on this map. Cited by 30 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Chronic Effects of Automated Mechanical Peripheral Stimulation on Cardiovascular and Functional Variables in Patients With Parkinson's Disease
Who cites it
30 citing papers in PubMed, 1 synthesis or guideline pooled it, 83 citations in OpenAlex.
- Management of Hypertension and Blood Pressure Dysregulation in Patients with Parkinson's Disease-a Systematic Review.Current hypertension reports · 2021Pooled it
- Cardiovascular autonomic dysfunction in Parkinson's disease: associations with disease severity and the modulatory role of dopaminergic therapy.Arquivos de neuro-psiquiatria · 2026Article
- Setting up an autonomic unit within the neurological department: a position statement of the European Federation of Autonomic Societies.Clinical autonomic research : official journal of the Clinical Autonomic Research Society · 2026Article
- Catecholaminergic storm and extreme blood pressure lability induced by combined levodopa/benserazide, selegiline, and piribedil in Parkinson's disease: a case report.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2026Article
- Relationship Between Morning Blood Pressure Surges and Peripheral Inflammatory Biomarkers in Parkinson's Disease.Biomedicines · 2025Article
- Identification of potentially causative drugs associated with hypotension: A scoping review.Archiv der Pharmazie · 2025Article
- The impacts of sex and the 5xFAD model of Alzheimer's disease on the sleep and spatial learning responses to feeding time.Frontiers in neurology · 2024Article
- Molecular characterization of the circadian clock in patients with Parkinson's disease-CLOCK4PD Study protocol.PloS one · 2024Article
- Circadian disruption and sleep disorders in neurodegeneration.Translational neurodegeneration · 2023Review
- Differentiated Embryo-Chondrocyte Expressed Gene1 and Parkinson's Disease: New Insights and Therapeutic Perspectives.Current neuropharmacology · 2023Review
- Association between hypotension during 24 h ambulatory blood pressure monitoring and reflex syncope: the SynABPM 1 study.European heart journal · 2022Article
- Sleep and circadian rhythms in Parkinson's disease and preclinical models.Molecular neurodegeneration · 2022Review
- 24-hour ambulatory blood pressure alterations in patients with Parkinson's disease.Brain and behavior · 2022Article
- Article
- Validation of Blood Pressure Measurement Using a Smartwatch in Patients With Parkinson's Disease.Frontiers in neurology · 2021Article
- Aortic stiffness and central systolic pressure are associated with ambulatory orthostatic BP fall in chronic kidney disease.Journal of nephrology · 2020Observational
- Circadian disruption and human health: A bidirectional relationship.The European journal of neuroscience · 2020Review
- Chronotherapies for Parkinson's disease.Progress in neurobiology · 2019Review
- Fatigue in Parkinson's Disease Associates with Lower Ambulatory Diastolic Blood Pressure.Journal of Parkinson's disease · 2019Article
- Impact of disease duration and cardiovascular dysautonomia on hypertension in Parkinson's disease.Journal of clinical hypertension (Greenwich, Conn.) · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Non-motor symptoms are now commonly recognized in Parkinson's disease (PD) and can include dysautonomia. Impairment of cardiovascular autonomic function can occur at any stage of PD but is typically prevalent in advanced stages or related to (anti-Parkinsonian) drugs and can result in atypical blood pressure (BP) readings and related symptoms such as orthostatic hypotension (OH) and supine hypertension. OH is usually diagnosed with a head-up-tilt test (HUT) or an (active) standing test (also known as Schellong test) in the laboratory, but 24 h ambulatory blood pressure monitoring (ABPM) in a home setting may have several advantages, such as providing an overview of symptoms in daily life alongside pathophysiology as well as assessment of treatment interventions. This, however, is only possible if ABPM is administrated correctly and an autonomic protocol (including a diary) is followed which will be discussed in this review. A 24-h ABPM does not only allow the detection of OH, if it is present, but also the assessment of cardiovascular autonomic dysfunction during and after various daily stimuli, such as postprandial and alcohol dependent hypotension, as well as exercise and drug induced hypotension. Furthermore, information about the circadian rhythm of BP and heart rate (HR) can be obtained and establish whether or not a patient has a fall of BP at night (i.e., "dipper" vs. non-"dipper"). The information about nocturnal BP may also allow the investigation or detection of disorders such as sleep dysfunction, nocturnal movement disorders, and obstructive sleep apnea, which are common in PD. Additionally, a 24-h ABPM should be conducted to examine the effectiveness of OH therapy. This review will outline the methodology of 24 h ABPM in PD, summarize findings of such studies in PD, and briefly consider common daily stimuli that might affect 24 h ABPM.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.