Evidence map›Paper›PMID 23720460›Full record

ReviewGlycobiology2013

A refined palate: bacterial consumption of host glycans in the gut.

Angela Marcobal, Audrey M Southwick, Kristen A Earle, Justin L Sonnenburg

Open access · bronzeAbstract readReview
In one paragraph

Review in Glycobiology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 110 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
110citing papers in PubMed, 1 pooled it
23.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

110 citing papers in PubMed, 1 synthesis or guideline pooled it, 179 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Review
  4. The VaginalMicroorganisms · 2026
    Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Characterization ofFrontiers in microbiology · 2025
    Article
  15. Article
  16. Review
  17. Review
  18. Sialic acid plays a pivotal role in licensingProceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  19. Poultry gut health and beyond.Animal nutrition (Zhongguo xu mu shou yi xue hui) · 2023
    Article
  20. Article

50 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Angela MarcobalDepartment of Microbiology and Immunology, Stanford University School of Medicine, Stanford, CA, USA.
Audrey M Southwick
Kristen A Earle
Justin L Sonnenburg
Stanford University · US

Funding

Impact of Diet on Intestinal Microbiota-Host DynamicsR01DK085025 · NIDDK · STANFORD UNIVERSITY · PI JUSTIN L SONNENBURG · 2010 to 2026
$6.4M
NIDDK NIH HHS DK085025
6 · The paper itself

Abstract

The human intestine houses a dense microbial ecosystem in which the struggle for nutrients creates a continual and dynamic selective force. Host-produced mucus glycans provide a ubiquitous source of carbon and energy for microbial species. Not surprisingly, many gut resident bacteria have become highly adapted to efficiently consume numerous distinct structures present in host glycans. We propose that sophistication in mucus consumption is a trait most likely to be found in gut residents that have co-evolved with hosts, microbes that have adapted to the complexity associated with the host glycan landscape.

Indexed as

BacteriaHumansIntestinal MucosaIntestinesPolysaccharidesPolysaccharidesgut microbiotahost-microbial interactionmicrobiomemucinpolysaccharide utilization

Identifiers

PMID23720460
PMCPMC3724412
OpenAlexW2107319829

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.