ArticleThe American journal of pathology1990
Immunohistochemical localization of antioxidant enzymes in adult Syrian hamster tissues and during kidney development.
Article in The American journal of pathology, 1990. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
28 citing papers in PubMed, 105 citations in OpenAlex.
- Testicular Expression of Antioxidant Enzymes and Changes in Response to a Slow-Release Deslorelin Implant (SuprelorinAnimals : an open access journal from MDPI · 2022Article
- Hydrogen Peroxide Mediates Artemisinin-Derived C-16 Carba-Dimer-Induced Toxicity of Human Cancer Cells.Antioxidants (Basel, Switzerland) · 2020Article
- Hormetic Property of Ginseng Steroids on Anti-Oxidant Status against Exercise Challenge in Rat Skeletal Muscle.Antioxidants (Basel, Switzerland) · 2017Article
- Modulation of cellular redox homeostasis by the endocannabinoid system.Open biology · 2016Review
- Manganese superoxide dismutase regulates a redox cycle within the cell cycle.Antioxidants & redox signaling · 2014Review
- Catalase prevents maternal diabetes-induced perinatal programming via the Nrf2-HO-1 defense system.Diabetes · 2012Article
- Redox control of the cell cycle in health and disease.Antioxidants & redox signaling · 2009Review
- Review
- A redox signature score identifies diffuse large B-cell lymphoma patients with a poor prognosis.Blood · 2005Article
- Metastatic progression of pancreatic cancer: changes in antioxidant enzymes and cell growth.Clinical & experimental metastasis · 2005Article
- Expression of Mn-Superoxide Dismutase Gene in Nontumorigenic and Tumorigenic Human Mammary Epithelial Cells.Journal of biomedicine & biotechnology · 2004Article
- Morphologic assessment of oxidative damage: A review.Journal of the American Aging Association · 2000Article
- Overexpression of human catalase inhibits proliferation and promotes apoptosis in vascular smooth muscle cells.Circulation research · 1999Article
- Overexpression of glia maturation factor in C6 cells promotes differentiation and activates superoxide dismutase.Neurochemical research · 1998Article
- Stable expression of manganese superoxide dismutase (MnSOD) in insulinoma cells prevents IL-1beta- induced cytotoxicity and reduces nitric oxide production.The Journal of clinical investigation · 1998Article
- Manganese superoxide dismutase protects nNOS neurons from NMDA and nitric oxide-mediated neurotoxicity.The Journal of neuroscience : the official journal of the Society for Neuroscience · 1998Review
- Article
- Effects of oxygen radicals and radical scavenging on opossum lower esophageal sphincter.Digestive diseases and sciences · 1997Article
- Immunohistochemical Characterization of Antioxidant Enzymes in Human Breast Cancer.Pathology oncology research : POR · 1997Article
- Copper/zinc superoxide dismutase expression in the human central nervous system. Correlation with selective neuronal vulnerability.The American journal of pathology · 1996Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
Abstract
Tissues from adult Syrian hamsters were studied with immunoperoxidase techniques using polyclonal antibodies to three antioxidant enzymes (copper, zinc and manganese forms of superoxide dismutase, and catalase). Tissues from labile organs, in which cell renewal is prominent (uterus, intestine, and transitional epithelium of the urinary tract), showed strong antioxidant enzyme immunostaining in differentiated cells but not in stem cells. In stable organs, in which cell renewal occurs at a high rate only in response to injury (kidney and adrenal), each cell type showed a specific pattern of antioxidant enzyme immunostaining. In permanent organs (brain and heart), antioxidant enzymes were regionally specific markers. Axons of the cerebellum showed more intense antioxidant enzyme staining than those of the cerebral cortex; in the heart, atria stained more intensely than ventricles. Germ cells of the testis resembled cell renewal systems in their antioxidant enzyme-immunostaining pattern: spermatogonia were negative, whereas spermatozoa were strongly positive. The tubules of the kidney showed no antioxidant enzyme immunostaining until after birth. Our results suggest that there is a prominent role for antioxidant enzymes in cell differentiation during development and cell renewal.
Indexed as
Identifiers
2372042PMC1877689W299127441What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.