Evidence map›Paper›PMID 23720377›Full record

ReviewEuropean heart journal. Cardiovascular Imaging2013

Image-guided therapies for myocardial repair: concepts and practical implementation.

Frank M Bengel, Richard T George, Karl H Schuleri, Albert C Lardo, Kai C Wollert

Open access · bronzeAbstract readReview
In one paragraph

Review in European heart journal. Cardiovascular Imaging, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.6field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 18 citations in OpenAlex.

  1. Review
  2. Multimodality Imaging of Inflammation and Ventricular Remodeling in Pressure-Overload Heart Failure.Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2020
    Article
  3. Emerging imaging targets for infiltrative cardiomyopathy: Inflammation and fibrosis.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2019
    Review
  4. PET-based myocardial efficiency: Powerful yet under-utilized-now simpler than ever.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2018
    Article
  5. Article
  6. Article
  7. Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Frank M BengelDepartment of Nuclear Medicine, Hannover Medical School, Carl-Neuberg-Str. 1, Hannover 30625, Germany. bengel.frank@mh-hannover.de
Richard T George
Karl H Schuleri
Albert C Lardo
Kai C Wollert
Johns Hopkins University · USMedizinische Hochschule Hannover · DEJohns Hopkins Medicine · US

Funding

Resynchronizing the Failing Heart: Insights from a Multiscale Cardiac ModelR01HL103428 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI TRAYANOVA, NATALIA A. · 2011 to 2014
$2.3M
NHLBI NIH HHS 1R01HL103428
6 · The paper itself

Abstract

Cell- and molecule-based therapeutic strategies to support wound healing and regeneration after myocardial infarction (MI) are under development. These emerging therapies aim at sustained preservation of ventricular function by enhancing tissue repair after myocardial ischaemia and reperfusion. Such therapies will benefit from guidance with regard to timing, regional targeting, suitable candidate selection, and effectiveness monitoring. Such guidance is effectively obtained by non-invasive tomographic imaging. Infarct size, tissue characteristics, muscle mass, and chamber geometry can be determined by magnetic resonance imaging and computed tomography. Radionuclide imaging can be used for the tracking of therapeutic agents and for the interrogation of molecular mechanisms such as inflammation, angiogenesis, and extracellular matrix activation. This review article portrays the hypothesis that an integrated approach with an early implementation of structural and molecular tomographic imaging in the development of novel therapies will provide a framework for achieving the goal of improved tissue repair after MI.

Indexed as

Tomography, X-Ray ComputedAnimalsBiomarkersContrast MediaHumansMagnetic Resonance Imaging, InterventionalMyocardial InfarctionMyocardiumRadiography, InterventionalBiomarkersContrast MediaAcute myocardial infarctionComputed tomographyMagnetic resonanceMolecular imagingMyocardial regenerationWound healing

Identifiers

PMID23720377
PMCPMC3859252
OpenAlexW2060361158

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.