Evidence map›Paper›PMID 23719305›Full record

ReviewClinics in perinatology2013

The biology of retinopathy of prematurity: how knowledge of pathogenesis guides treatment.

Lois E Smith, Anna-Lena Hard, Ann Hellström

Abstract readReview
In one paragraph

Review in Clinics in perinatology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
51citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

51 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Achieved oxygen saturations and retinopathy of prematurity in extreme preterms.Archives of disease in childhood. Fetal and neonatal edition · 2020
    Trial
  4. Trial
  5. Trial
  6. Article
  7. Article
  8. Review
  9. Review
  10. Review
  11. Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Mesenchymal stromal cell extracellular vesicles improve lung development in mechanically ventilated preterm lambs.American journal of physiology. Lung cellular and molecular physiology · 2024
    Article
  17. Article
  18. Review
  19. A review on retinopathy of prematurity.Medical hypothesis, discovery & innovation ophthalmology journal · 2024
    Review
  20. Cord blood transforming growth factor-β-induced as predictive biomarker of retinopathy of prematurity in preterm infants.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Lois E SmithDepartment of Ophthalmology, Children's Hospital Boston, Harvard Medical School, Boston, MA 02115, USA. Lois.Smith@childrens.harvard.edu
Anna-Lena Hard
Ann Hellström

Funding

SYNAPTIC MECHANISMS IN HIPPOCAMPAL EPILEPTOGENESISP30HD018655 · NICHD · CHILDREN'S HOSPITAL BOSTON · PI POMEROY, SCOTT LOREN · 1985 to 2015
$26.2M
Dietary control of angiogenesis in retinopathy modelsR01EY017017 · NEI · BOSTON CHILDREN'S HOSPITAL · PI Zhongjie Fu, Lois Smith · 2006 to 2026
$11.8M
Neuronal guidance molecules control revascularization in retinopathyR01EY022275 · NEI · BOSTON CHILDREN'S HOSPITAL · PI SMITH, LOIS · 2012 to 2014
$1.3M
NEI NIH HHS NEI EY017017NEI NIH HHS NEI EY022275NEI NIH HHS R01 EY017017NEI NIH HHS R01 EY022275NICHD NIH HHS P01 HD18655NICHD NIH HHS P30 HD018655
6 · The paper itself

Abstract

Retinopathy of prematurity occurs because the retina of a preterm infant at birth is incompletely vascularized, and if the postnatal environment does not match the in utero environment that supported retinal development, the vessels and neural retina will not grow normally. Risk factors determined from many clinical studies and animal studies fall into 2 categories: prenatal factors and postnatal factors.

Indexed as

ErythropoietinHumansInfantInfant, NewbornInfant, PrematureInsulin-Like Growth Factor IOxygenRetinaRetinopathy of PrematurityVascular Endothelial Growth Factor AErythropoietinInsulin-Like Growth Factor IOxygenVascular Endothelial Growth Factor A

Identifiers

PMID23719305
PMCPMC3673697

What OpenQuestion holds

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LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.