ArticleJournal of neurophysiology2013
Hearing loss differentially affects thalamic drive to two cortical interneuron subtypes.
Article in Journal of neurophysiology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.
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Who cites it
38 citing papers in PubMed.
- Synaptic zinc plasticity shapes adaptive and maladaptive cortical plasticity following cochlear injury.Science advances · 2026Article
- A computational theory of short-term synaptic plasticity: synapses learn to tell time.Research square · 2026Article
- Auditory cortical forward masking effects in squirrel monkeys with unilateral noise-induced hearing loss.Hearing research · 2026Article
- Layer 6 is a hub for cholinergic modulation in the mouse auditory cortex.Cerebral cortex (New York, N.Y. : 1991) · 2026Article
- Cell type-specific plasticity in synaptic, intrinsic, and sound response properties of deep-layer cortical neurons after noise trauma.Science advances · 2025Article
- Article
- Layer 6 is a hub for cholinergic modulation in the mouse auditory cortex.bioRxiv : the preprint server for biology · 2025Article
- Cell-type-specific plasticity of inhibitory interneurons in the rehabilitation of auditory cortex after peripheral damage.Nature communications · 2023Article
- Somatostatin-expressing interneurons modulate neocortical network through GABAb receptors in a synapse-specific manner.Scientific reports · 2023Article
- A Role for KCNQ Channels on Cell Type-Specific Plasticity in Mouse Auditory Cortex after Peripheral Damage.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2023Article
- A Redundant Cortical Code for Speech Envelope.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2023Article
- Offset Responses in the Auditory Cortex Show Unique History Dependence.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2022Article
- Development of Auditory Cortex Circuits.Journal of the Association for Research in Otolaryngology : JARO · 2021Review
- Article
- Differential Short-Term Plasticity of PV and SST Neurons Accounts for Adaptation and Facilitation of Cortical Neurons to Auditory Tones.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2020Article
- Visualising the topography of the acoustic radiation in clinical diffusion tensor imaging scans.Neuroradiology · 2020Article
- Structural neuroimaging of the altered brain stemming from pediatric and adolescent hearing loss-Scientific and clinical challenges.Wiley interdisciplinary reviews. Systems biology and medicine · 2020Review
- Stability in the Face of Change: Lifelong Experience-Dependent Plasticity in the Sensory Cortex.Frontiers in cellular neuroscience · 2020Article
- Early Auditory Experience Modifies Neuronal Firing Properties in the Zebra Finch Auditory Cortex.Frontiers in neural circuits · 2020Article
- Tinnitus Correlates with Downregulation of Cortical Glutamate Decarboxylase 65 Expression But Not Auditory Cortical Map Reorganization.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2019Article
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
Sensory deprivation, such as developmental hearing loss, leads to an adjustment of synaptic and membrane properties throughout the central nervous system. These changes are thought to compensate for diminished sound-evoked activity. This model predicts that compensatory changes should be synergistic with one another along each functional pathway. To test this idea, we examined the excitatory thalamic drive to two types of cortical inhibitory interneurons that display differential effects in response to developmental hearing loss. The inhibitory synapses made by fast-spiking (FS) cells are weakened by hearing loss, whereas those made by low threshold-spiking (LTS) cells remain strong but display greater short-term depression (Takesian et al. 2010). Whole-cell recordings were made from FS or LTS interneurons in a thalamocortical brain slice, and medial geniculate (MG)-evoked postsynaptic potentials were analyzed. Following hearing loss, MG-evoked net excitatory potentials were smaller than normal at FS cells but larger than normal at LTS cells. Furthermore, MG-evoked excitatory potentials displayed less short-term depression at FS cells and greater short-term depression at LTS cells. Thus deprivation-induced adjustments of excitatory synapses onto inhibitory interneurons are cell-type specific and parallel the changes made by the inhibitory afferents.
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Registered trials
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