Evidence map›Paper›PMID 23719159›Full record

ArticleNeuron2013

Mapping and cracking sensorimotor circuits in genetic model organisms.

Damon A Clark, Limor Freifeld, Thomas R Clandinin

Abstract read
In one paragraph

Article in Neuron, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed.

  1. Article
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  7. Thermotaxis in an apolar, non-neuronal animal.Journal of the Royal Society, Interface · 2023
    Article
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  11. Review
  12. Article
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  15. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Damon A ClarkDepartment of Neurobiology, 299 W. Campus Drive, Stanford University, Stanford, CA 94305, USA.
Limor Freifeld
Thomas R Clandinin

Funding

Dissecting the functional anatomy of the visual system: a new way forwardDP1OD003530 · OD · STANFORD UNIVERSITY · PI CLANDININ, THOMAS ROBERT · 2007 to 2011
$3.9M
Dissecting Neural Circuit Computations in the Peripheral Visual SystemR01EY022638 · NEI · STANFORD UNIVERSITY · PI CLANDININ, THOMAS ROBERT · 2012 to 2021
$3.5M
NEI NIH HHS R01 EY022638NIH HHS DP1 OD003530
6 · The paper itself

Abstract

One central goal of systems neuroscience is to understand how neural circuits implement the computations that link sensory inputs to behavior. Work combining electrophysiological and imaging-based approaches to measure neural activity with pharmacological and electrophysiological manipulations has provided fundamental insights. More recently, genetic approaches have been used to monitor and manipulate neural activity, opening up new experimental opportunities and challenges. Here, we discuss issues associated with applying genetic approaches to circuit dissection in sensorimotor transformations, outlining important considerations for experimental design and considering how modeling can complement experimental approaches.

Indexed as

Transcription, GeneticAnimalsBehaviorBehavior, AnimalBrainModels, AnimalModels, GeneticNerve Tissue ProteinsNeural PathwaysNeurosciencesPerceptionReaction TimeSensationSignal TransductionSystems BiologyNerve Tissue Proteins

Identifiers

PMID23719159
PMCPMC4023671

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.