Evidence map›Paper›PMID 23718723›Full record

Observational studyCritical care (London, England)2013

Subclavian central venous catheter-related thrombosis in trauma patients: incidence, risk factors and influence of polyurethane type.

Ariane Gentile, Laurent Petit, Françoise Masson, Vincent Cottenceau, Josseline Bertrand-Barat, Geneviève Freyburger, Catherine Pinaquy, Alain Léger, Jean-François Cochard, François Sztark

Registry-linked trialOpen access · goldAbstract readObservational Study
In one paragraph

Observational study in Critical care (London, England), 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03327376 (Daily Ultrasound-screening for CVC-related Thrombosis in Intensive Care Patients), which is not on this map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
3.3field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03327376 completednot on this mapstarted 2017, after this paper: background citation

Daily Ultrasound-screening for CVC-related Thrombosis in Intensive Care Patients

TypeobservationalSponsorSecond Affiliated Hospital, Zhejiang University, School of MedicineRan2017 to 2022Enrolled1,262ConditionsCentral Venous Catheter Thrombosis, Critical Illness, UltrasonographyArmsultrasound-screening
3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Review
  5. Article
  6. Article
  7. Central venous catheter-related thrombosis in senile male patients: New risk factors and predictors.Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban · 2015
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Ariane Gentile
Laurent Petit
Françoise Masson
Vincent Cottenceau
Josseline Bertrand-Barat
Geneviève Freyburger
Catherine Pinaquy
Alain Léger
Jean-François Cochard
François Sztark
Hôpital Pellegrin · FRCentre Hospitalier Universitaire de Bordeaux · FRInserm · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe incidence of deep venous thrombosis (DVT) related to a central venous catheter varies considerably in ICUs depending on the population included. The aim of this study was to determine subclavian central venous catheter (SCVC)-related DVT risk factors in severely traumatized patients with regard to two kinds of polyurethane catheters.

methodsCritically ill trauma patients needing a SCVC for their usual care were prospectively included in an observational study. Depending on the month of inclusion, patients received one of the two available products in the emergency unit: either an aromatic polyurethane SCVC or an aliphatic polyurethane SCVC. Patients were screened weekly by ultrasound for SCVC-related DVT. Potential risk factors were collected, including history-related, trauma-related and SCVC-related characteristics.

resultsA total of 186 patients were included with a median Injury Severity Sore of 30 and a high rate of severe brain injuries (21% of high intracranial pressure). Incidence of SCVC-related DVT was 37% (95% confidence interval: 26 to 40) in patients or 20/1,000 catheter-days. SCVC-related DVT occurred within 8 days in 65% of cases. There was no significant difference in DVT rates between the aromatic polyurethane and aliphatic polyurethane SCVC groups (38% vs. 36%). SCVC-related DVT independent risk factors were age>30 years, intracranial hypertension, massive transfusion (>10 packed red blood cell units), SCVC tip position in the internal jugular or in the innominate vein, and ipsilateral jugular catheter.

conclusionSCVC-related DVT concerned one-third of these severely traumatized patients and was mostly clinically silent. Incidence did not depend on the type of polyurethane but was related to age>30 years, intracranial hypertension or misplacement of the SCVC. Further studies are needed to assess the cost-effectiveness of routine screening in these patients in whom thromboprophylaxis may be hazardous.

Indexed as

Subclavian VeinAdultCentral Venous CathetersFemaleHumansIncidenceMaleMiddle AgedPolyurethanesProspective StudiesRisk FactorsVenous ThrombosisWounds and InjuriesYoung AdultPolyurethanes

Identifiers

PMID23718723
PMCPMC4056006
OpenAlexW2118669997

What OpenQuestion holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.