ArticlePloS one2013
Proper indication of BRAF(V600E) mutation testing in fine-needle aspirates of thyroid nodules.
Article in PloS one, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 3 of them syntheses that pooled it.
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Who cites it
14 citing papers in PubMed, 3 syntheses or guidelines pooled it, 28 citations in OpenAlex.
- Testing for BRAF (V600E) Mutation in Thyroid Nodules with Fine-Needle Aspiration (FNA) Read as Suspicious for Malignancy (Bethesda V, Thy4, TIR4): a Systematic Review and Meta-analysis.Endocrine pathology · 2020Pooled it
- Molecular Variants and Their Risks for Malignancy in Cytologically Indeterminate Thyroid Nodules.Thyroid : official journal of the American Thyroid Association · 2019Pooled it
- Comparative analysis of diagnostic performance, feasibility and cost of different test-methods for thyroid nodules with indeterminate cytology.Oncotarget · 2017Pooled it
- Exploring somatic mutations inFrontiers in pharmacology · 2024Article
- Implications of US radiomics signature for predicting malignancy in thyroid nodules with indeterminate cytology.European radiology · 2021Article
- Diagnostic Efficacy of Ultrasound, Cytology, and BRAFFrontiers in oncology · 2021Article
- Molecular markers for the classification of cytologically indeterminate thyroid nodules.Journal of endocrinological investigation · 2020Review
- Value ofAJNR. American journal of neuroradiology · 2018Article
- Article
- Relationship BetweenWorld journal of surgery · 2018Article
- Diagnostic value of BRAF (V600E)-mutation analysis in fine-needle aspiration of thyroid nodules: a meta-analysis.OncoTargets and therapy · 2016Article
- High-Resolution Melting Is a Sensitive, Cost-Effective, Time-Saving Technique for BRAF V600E Detection in Thyroid FNAB Washing Liquid: A Prospective Cohort Study.European thyroid journal · 2015Article
- Article
- Fine-needle Aspiration Washout Precipitation Specimens: An Acceptable Supplement to Genetic Mutation Detection of Thyroid Nodules.Technology in cancer research & treatmentArticle
Corrections and comments
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe aim of this study was to evaluate the proper indication of adjunctive BRAF(V600E) mutation analysis at the time of ultrasound-guided fine-needle aspiration in the diagnosis of thyroid nodules.
methodsThis study included 518 nodules in 479 patients who underwent ultrasound-guided fine-needle aspiration with BRAF(V600E) mutation. We calculated and compared the diagnostic performances of cytology and cytology with BRAF(V600E) mutation analysis to detect malignancy among thyroid nodules according to ultrasound features and size.
resultsSensitivity, negative predictive value, and accuracy of cytology with BRAF(V600E) mutation analysis were significantly higher than those of cytology alone in thyroid nodules with suspicious ultrasound features, regardless of size. Diagnostic performances did not show significant differences between cytology and cytology with BRAF(V600E) mutation analysis in nodules without any suspicious ultrasound features, regardless of size.
conclusionThe BRAF(V600E) mutation analysis was a useful adjunctive diagnostic tool in the diagnosis of thyroid nodules with suspicious ultrasound features regardless of size.
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