ArticleFrontiers in microbiology2013
Enzymes involved in the anaerobic oxidation of n-alkanes: from methane to long-chain paraffins.
Article in Frontiers in microbiology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers.
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47 citing papers in PubMed, 131 citations in OpenAlex.
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- Metapangenomic investigation provides insight into niche differentiation of methanogenic populations from the subsurface serpentinizing environment, Samail Ophiolite, Oman.Frontiers in microbiology · 2023Article
- A Structural View of Alkyl-Coenzyme M Reductases, the First Step of Alkane Anaerobic Oxidation Catalyzed by Archaea.Biochemistry · 2022Review
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- A review on microbial diversity and genetic markers involved in methanogenic degradation of hydrocarbons: futuristic prospects of biofuel recovery from contaminated regions.Environmental science and pollution research international · 2021Review
- Methanogenic Biodegradation ofMicroorganisms · 2021Article
- Change in microbial profile and environmental conditions in a constructed wetland system treating greywater.Environmental science and pollution research international · 2021Article
- New evidence for a hydroxylation pathway for anaerobic alkane degradation supported by analyses of functional genes and signature metabolites in oil reservoirs.AMB Express · 2021Article
- Combined Use of Diagnostic Fumarate Addition Metabolites and Genes Provides Evidence for Anaerobic Hydrocarbon Biodegradation in Contaminated Groundwater.Microorganisms · 2020Article
- Protective Role of Bacterial Alkanesulfonate Monooxygenase under Oxidative Stress.Applied and environmental microbiology · 2020Article
- Long-chain n-alkane biodegradation coupling to methane production in an enriched culture from production water of a high-temperature oil reservoir.AMB Express · 2020Article
- Methanogenic biodegradation of CAMB Express · 2020Article
- The Expanding Role of Methyl-Coenzyme M Reductase in the Anaerobic Functionalization of Alkanes.Biochemistry · 2019Article
- Methanogenic Degradation of LongApplied and environmental microbiology · 2019Article
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1 author at 1 institution in 1 country.
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Abstract
Anaerobic microorganisms play key roles in the biogeochemical cycling of methane and non-methane alkanes. To date, there appear to be at least three proposed mechanisms of anaerobic methane oxidation (AOM). The first pathway is mediated by consortia of archaeal anaerobic methane oxidizers and sulfate-reducing bacteria (SRB) via "reverse methanogenesis" and is catalyzed by a homolog of methyl-coenzyme M reductase. The second pathway is also mediated by anaerobic methane oxidizers and SRB, wherein the archaeal members catalyze both methane oxidation and sulfate reduction and zero-valent sulfur is a key intermediate. The third AOM mechanism is a nitrite-dependent, "intra-aerobic" pathway described for the denitrifying bacterium, 'Candidatus Methylomirabilis oxyfera.' It is hypothesized that AOM proceeds via reduction of nitrite to nitric oxide, followed by the conversion of two nitric oxide molecules to dinitrogen and molecular oxygen. The latter can be used to functionalize the methane via a particulate methane monooxygenase. With respect to non-methane alkanes, there also appear to be novel mechanisms of activation. The most well-described pathway is the addition of non-methane alkanes across the double bond of fumarate to form alkyl-substituted succinates via the putative glycyl radical enzyme, alkylsuccinate synthase (also known as methylalkylsuccinate synthase). Other proposed mechanisms include anaerobic hydroxylation via ethylbenzene dehydrogenase-like enzymes and an "intra-aerobic" denitrification pathway similar to that described for 'Methylomirabilis oxyfera.'
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