ArticleFrontiers in psychology2013
Schizophrenia and visual backward masking: a general deficit of target enhancement.
Article in Frontiers in psychology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
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Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Rethinking Body Ownership in Schizophrenia: Experimental and Meta-analytical Approaches Show no Evidence for Deficits.Schizophrenia bulletin · 2018Pooled it
- Examining the diametric model of autistic and psychotic traits through temporal perception.Scientific reports · 2026Article
- Understanding visual perception in visual snow syndrome: a battery of psychophysical tests plus the 30-day clinical diary.Brain communications · 2024Article
- Perceptual Functioning.Current topics in behavioral neurosciences · 2023Article
- Embedded figures in schizophrenia: A main deficit but no specificity.Schizophrenia research. Cognition · 2022Article
- Early-stage visual perception impairment in schizophrenia, bottom-up and back again.Schizophrenia (Heidelberg, Germany) · 2022Review
- Saccadic suppression in schizophrenia.Scientific reports · 2021Article
- Disruption of Conscious Access in Psychosis Is Associated with Altered Structural Brain Connectivity.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2021Article
- Neural Compensation Mechanisms of Siblings of Schizophrenia Patients as Revealed by High-Density EEG.Schizophrenia bulletin · 2020Article
- Examining motion speed processing in schizophrenia using the flash lag illusion.Schizophrenia research. Cognition · 2020Article
- Tobacco Use Decreases Visual Sensitivity in Schizophrenia.Frontiers in psychology · 2018Article
- Spatial and temporal aspects of visual backward masking in children and young adolescents.Attention, perception & psychophysics · 2016Article
- Ageing and visual spatiotemporal processing.Experimental brain research · 2015Article
- Does chronic nicotine consumption influence visual backward masking in schizophrenia and schizotypy?Schizophrenia research. Cognition · 2015Article
- Disruption of information processing in schizophrenia: The time perspective.Schizophrenia research. Cognition · 2015Review
- Visual masking & schizophrenia.Schizophrenia research. Cognition · 2015Review
- Vision in schizophrenia: why it matters.Frontiers in psychology · 2015Article
- Enhanced distraction by magnocellular salience signals in schizophrenia.Neuropsychologia · 2014Article
- Association of the Nicotinic Receptor α7 Subunit Gene (CHRNA7) with Schizophrenia and Visual Backward Masking.Frontiers in psychiatry · 2013Article
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4 authors.
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No grant is acknowledged in the PubMed record.
Abstract
The obvious symptoms of schizophrenia are of cognitive and psychopathological nature. However, schizophrenia affects also visual processing which becomes particularly evident when stimuli are presented for short durations and are followed by a masking stimulus. Visual deficits are of great interest because they might be related to the genetic variations underlying the disease (endophenotype concept). Visual masking deficits are usually attributed to specific dysfunctions of the visual system such as a hypo- or hyper-active magnocellular system. Here, we propose that visual deficits are a manifestation of a general deficit related to the enhancement of weak neural signals as occurring in all other sorts of information processing. We summarize previous findings with the shine-through masking paradigm where a shortly presented vernier target is followed by a masking grating. The mask deteriorates visual processing of schizophrenic patients by almost an order of magnitude compared to healthy controls. We propose that these deficits are caused by dysfunctions of attention and the cholinergic system leading to weak neural activity corresponding to the vernier. High density electrophysiological recordings (EEG) show that indeed neural activity is strongly reduced in schizophrenic patients which we attribute to the lack of vernier enhancement. When only the masking grating is presented, EEG responses are roughly comparable between patients and control. Our hypothesis is supported by findings relating visual masking to genetic deviants of the nicotinic α7 receptor (CHRNA7).
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