ArticleFrontiers in human neuroscience2013
The role of D4 receptor gene exon III polymorphisms in shaping human altruism and prosocial behavior.
Article in Frontiers in human neuroscience, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 29 citations in OpenAlex.
- Article
- Genetic variation of dopamine and serotonin function modulates the feedback-related negativity during altruistic punishment.Scientific reports · 2017Article
- Genetic polymorphisms between altruism and selfishness close to the Hamilton thresholdRoyal Society open science · 2017Article
- Measuring Prosocial Tendencies in Germany: Sources of Validity and Reliablity of the Revised Prosocial Tendency Measure.Frontiers in psychology · 2017Article
- Men increase contributions to a public good when under sexual competition.Scientific reports · 2016Article
- Dopamine-System Genes and Cultural Acquisition: The Norm Sensitivity Hypothesis.Current opinion in psychology · 2016Article
- Molecular Signatures of Natural Selection for Polymorphic Genes of the Human Dopaminergic and Serotonergic Systems: A Review.Frontiers in psychology · 2016Review
- Association between the dopamine D4 receptor gene exon III variable number of tandem repeats and political attitudes in female Han Chinese.Proceedings. Biological sciences · 2015Article
- Peer Victimization and DRD4 Genotype Influence Problem Behaviors in Young Children.Journal of youth and adolescence · 2015Article
- DRD4 Genotype and the Developmental Link of Peer Social Preference with Conduct Problems and Prosocial Behavior Across Ages 9-12 Years.Journal of youth and adolescence · 2015Article
- Dopamine D4 receptor gene and religious affiliation correlate with dictator game altruism in males and not females: evidence for gender-sensitive gene × culture interaction.Frontiers in neuroscience · 2015Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Human beings are an extraordinarily altruistic species often willing to help strangers at a considerable cost (sometimes life itself) to themselves. But as Darwin noted "… he who was ready to sacrifice his life, as many a savage has been, rather than betray his comrades, would often leave no offspring to inherit his noble nature." Hence, this is the paradox of altruism. Twin studies have shown that altruism and other prosocial behavior show considerable heritability and more recently a number of candidate genes have been identified with this phenotype. Among these first provisional findings are genes encoding elements of dopaminergic transmission. In this article we will review the evidence for the involvement of one of these, the dopamine D4 receptor (DRD4) gene, in shaping human prosocial behavior and consider the methodologies employed in measuring this trait, specific molecular genetic findings and finally, evidence from several Gene × Environment (G × E) studies that imply differential susceptibility of this gene to environmental influences.
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