ArticleJournal of ginseng research2013
Ginseng for managing menopause symptoms: a systematic review of randomized clinical trials.
Article in Journal of ginseng research, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Efficacy of Hormonal and Non-Hormonal Vaginal Gel Preparations on the Female Sexual Satisfaction Index in Postmenopausal Women with Sexual Dysfunction Syndrome:Sultan Qaboos University medical journal · 2025Pooled it
- Ginseng for managing menopausal woman's health: A systematic review of double-blind, randomized, placebo-controlled trials.Medicine · 2016Pooled it
- Neurokinin receptor antagonists for vasomotor symptoms: from KNDy neurons to clinical translation.Nature reviews. Endocrinology · 2026Review
- Potential ofChinese herbal medicines · 2025Review
- The effect of ginseng on sexual function in postmenopausal women with major depression: a triple-blind randomized controlled trial.Journal of pharmaceutical health care and sciences · 2025Article
- Challenges in phytotherapy research.Frontiers in pharmacology · 2023Article
- The effect of ginsenosides on depression in preclinical studies: A systematic review and meta-analysis.Journal of ginseng research · 2021Article
- Antihypertensive effects of Korean wild simulated ginseng (Sanyangsam) extracts in spontaneously hypertensive rats.Food science and biotechnology · 2019Article
- Effect of the Mixed Herbal Medicines Extract (Fennel, Chamomile, and Saffron) on Menopause Syndrome: a Randomized Controlled Clinical Trial.Journal of caring sciences · 2019Article
- Effects of ginseng on two main sex steroid hormone receptors: estrogen and androgen receptors.Journal of ginseng research · 2017Review
- Improved oral bioavailability of 20(R)-25-methoxyl-dammarane-3β, 12β, 20-triol using nanoemulsion based on phospholipid complex: design, characterization, and in vivo pharmacokinetics in rats.Drug design, development and therapy · 2016Article
- Review of cases of patient risk associated with ginseng abuse and misuse.Journal of ginseng research · 2015Review
- Is complementary and alternative therapy effective for women in the climacteric period?Journal of menopausal medicine · 2015Review
- Anti-inflammatory activity of AP-SF, a ginsenoside-enriched fraction, from Korean ginseng.Journal of ginseng research · 2015Article
- Dietary supplementation of chinese ginseng prevents obesity and metabolic syndrome in high-fat diet-fed mice.Journal of medicinal food · 2014Article
- The use of dietary supplements to alleviate androgen deprivation therapy side effects during prostate cancer treatment.Nutrients · 2014Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The aim of this review was to assess the effectiveness of ginseng as a treatment option for managing menopause symptoms. We searched the literature using 11 databases from their inception to 26 September 2012 and included all randomized clinical trials (RCTs) that compared any type of ginseng to a placebo controls in postmenopausal women. The methodological quality of all studies was assessed using a Cochrane risk of bias tool. Four RCTs met our inclusion criteria. Most RCTs had high risk of bias. One RCT showed that Korean red ginseng (KRG) significantly improved sexual arousal and global health compared with placebo. Another RCT reported the superiority of KRG over placebo for treating menopause symptoms on Kupperman's index and menopausal rating score. The third RCT failed to show a significant effect of KRG on hot flash frequency compared to placebo. The fourth RCT found beneficial effects of ginseng compared to placebo on depression and well-being. In conclusion, the evidence on ginseng as an effective treatment for managing menopause symptoms is limited. Most of the RCTs are burdened with a high risk of bias. Thus firm conclusions cannot be drawn. Rigorous studies seem warranted.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.