ArticleAnnals of dermatology2013
Extramammary paget disease: minimal surgical therapy.
Article in Annals of dermatology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
9 citing papers in PubMed, 27 citations in OpenAlex.
- Factors Related to Recurrence Rates of Extramammary Paget Disease: A Case Series and Literature Review.Archives of plastic surgery · 2026Article
- Review
- A Systematic Review and Meta-Analysis of Mapping Biopsy for Primary Extramammary Paget's Disease in Reducing Recurrence Following Surgical Excision.Annals of surgery open : perspectives of surgical history, education, and clinical approaches · 2023Article
- Topical Imiquimod in Primary Cutaneous Extramammary Paget's Disease: A Systematic Review.Cancers · 2023Review
- Review
- Medical and Surgical Strategies in Vulvar Paget Disease: Let's Throw Some Light!Journal of personalized medicine · 2023Review
- Surgical Treatment for Extramammary Paget's Disease.Current treatment options in oncology · 2018Review
- Successful treatment of areolar Fox-Fordyce disease with surgical excision and 1550-nm fractionated erbium glass laser.International wound journal · 2016Article
- Efficacy of 5% imiquimod cream on vulvar intraepithelial neoplasia in Korea: pilot study.Annals of dermatology · 2015Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundExtramammary Paget disease (EMPD) is an uncommon malignant neoplasm affecting apocrine gland-bearing skin which usually occurs in the anogenital area of patients older than 50 years. Although Mohs micrographic surgery (MMS) is recommended for the treatment of EMPD, wide local excision has also been performed by many other surgeons including dermatosurgeons. However, the extent of an adequate resection margin is still under debate.
objectiveThe efficacy of minimal surgical therapy consisting of a wide excision combined with preoperative multiple scouting biopsies and postoperative topical imiquimod was investigated for the treatment of EMPD in Korean patients.
methodsBetween 2006 and 2012, 10 patients with primary EMPD were treated with wide surgical excision, with a surgical margin of less than 2.5 cm. Multiple preoperative scouting biopsies and postoperative topical imiquimod were also performed to delineate the lesional boundaries and to reduce the recurrence rate.
resultsDuring the 6-year follow-up period, complications and recurrences were not observed.
conclusionMinimal surgical therapy may be an effective alternative when MMS is unavailable.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.