Evidence map›Paper›PMID 23716940›Full record

ArticleIndian journal of human genetics2012

The low frequency of Y chromosome microdeletions in subfertile males in a Sinhalese population of Sri Lanka.

Tithila Kalum Wettasinghe, Rohan W Jayasekara, Vajira H W Dissanayake

Abstract read
In one paragraph

Article in Indian journal of human genetics, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Tithila Kalum WettasingheHuman Genetics Unit, Faculty of Medicine, University of Colombo, Colombo, Sri Lanka.
Rohan W Jayasekara
Vajira H W Dissanayake

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsThis study was designed to determine the prevalence of azoospermia factor (AZF) microdeletions on the Y chromosome in Sri Lankan Sinhalese infertile men with azoospermia and severe oligozoospermia. SETTINGS AND

designThe patient group was 207 karyotypically normal infertile Sinhalese males. MATERIALS AND

methodsThe presence of 13 sequence-tagged site (STS) markers in the AZF region was tested using multiplex polymerase chain reaction (M-PCR). One hundred and twenty unselected men were also studied as a control group.

resultsThree (1.5%) had classic Y chromosome microdeletions in the AZFc sub-region.

conclusionsThese results suggest a much lower Y chromosome microdeletion frequency than previously thought, even among a strictly selected group of sub-fertile males in Sri Lanka.

Indexed as

Azoospermia factor aazoospermia factor bazoospermia factor cmale factor sub-fertilityY-chromosome microdeletions

Identifiers

PMID23716940
PMCPMC3656521

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.