ArticleIndian journal of human genetics2012
Hemoglobinopathies in South Gujarat population and incidence of anemia in them.
Article in Indian journal of human genetics, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
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Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it, 43 citations in OpenAlex.
- Systematic Review and Meta-analysis on the Prevalence of Common Hemoglobinopathies in India.Annals of African medicine · 2026Pooled it
- Haemoglobin D-Punjab haemoglobinopathy, the silent epidemic: A prospective hospital based study in Gujarat, India.Bioinformation · 2026Article
- Article
- Assessing anemia burden and multifactorial contributors among pregnant women in Gujarat: a cross-sectional study integrating biochemical, nutritional, and geographic disparities.Frontiers in global women's health · 2025Article
- Prevalence of beta thalassemia carriers in India: a systematic review and meta-analysis.Journal of community genetics · 2023Review
- Systematic Literature Review Shows Gaps in Data on Global Prevalence and Birth Prevalence of Sickle Cell Disease and Sickle Cell Trait: Call for Action to Scale Up and Harmonize Data Collection.Journal of clinical medicine · 2023Review
- Screening of Extended Family Members of Thalassemia Major Children as a Thalassemia Preventive Strategy.Ethiopian journal of health sciences · 2022Article
- Undiagnosed haemoglobinopathies among pregnant women attending antenatal care clinics in Pune, India.Journal of community genetics · 2021Article
- Seroprevalence of HBV, HCV and HIV-1 and Correlation with Molecular Markers among Multi-Transfused Thalassemia Patients in Western India.Mediterranean journal of hematology and infectious diseases · 2020Article
- Phenotyping of Rh, Kell, Duffy and Kidd Blood Group Antigens among Non-Tribal and Tribal Population of South Gujarat and its Implication in Preventing Alloimmunization in Multitransfused Patients.Mediterranean journal of hematology and infectious diseases · 2018Article
- Haemoglobinopathies and β-Thalassaemia among the Tribals Working in the Tea Gardens of Assam, India.Journal of clinical and diagnostic research : JCDR · 2016Article
- Sickle cell disease in tribal populations in India.The Indian journal of medical research · 2015Article
- Epistasis and the sensitivity of phenotypic screens for beta thalassaemia.British journal of haematology · 2015Review
- Challenges Associated with the Identification of Abnormal Hemoglobin Variants Utilizing the High-performance Liquid Chromatograph Technique: A Prospective Study in a Hospital Setting in Gujarat.International journal of applied & basic medical researchArticle
- Tackling the Menace of Anemia and Hemoglobinopathies among Young Adults - Conceptualizing University-Level Screening.Indian journal of community medicine : official publication of Indian Association of Preventive & Social MedicineArticle
- Situational Analysis of Sickle Cell Disease in Gujarat, India.Indian journal of community medicine : official publication of Indian Association of Preventive & Social MedicineArticle
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo Screen of South Gujarat population for determination of prevalence of different hemoglobinopathies particularly beta thalassemia trait (BTT) and sickle cell trait (SCT) and find out the incidence of anemia in them. MATERIAL AND
methodsThe present study screened 32,857 samples of students from different school and colleges in South Gujarat. Blood samples were initially tested for solubility test and complete hemogram on hematology analyzer. Samples having MCV (≤78), MCH (≤28) and/or positive solubility test were investigated for Hb electrophoresis on cellulose acetate membrane (pH 8.6). Hb A2 level ≥3.5% was considered as diagnostic for BTT. High performance liquid chromatography on Biorad Hb variant system was done on samples having doubtful results.
resultOverall prevalence of BTT and SCT in South Gujarat was 4.4% and 1.3% respectively. Gamit, Vasava, Chaudhary, and Mahyavanshi castes had high prevalence of BTT (15.9%, 13.6%, 12.6%, and 6.9%) as well as SCT (22.2%, 15.2, 22.3, and 4.2%) respectively. Other communities like Lohana (10.8%), Sindhi (10.2%), Prajapati (6.3%), and Ghanchi (6.2%) also showed higher prevalence of BTT. Incidence of mild to moderate anemia was higher in BTT and SCT compared to non-BTT or non-SCT subjects.
conclusionStudy suggests that BTT is the most prevalent hemoglobinopathy in South Gujarat. β-thalassemia and Sickle cell anemia are highly prevalent in Mahyavanshi, Chaudhary, Gamit, Vasava and Rohit. Prajapati, Lohana, Leva Patel, and Ghanchi have β- thalassemia risk. SCT is more frequently detected in Dhodia Patel and Kukanas.
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