ArticleEuropean child & adolescent psychiatry2014
Response time intra-subject variability: commonalities between children with autism spectrum disorders and children with ADHD.
Article in European child & adolescent psychiatry, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
26 citing papers in PubMed, 1 synthesis or guideline pooled it, 54 citations in OpenAlex.
- The Prevalence of Attention Deficit/Hyperactivity Disorder Symptoms in Children and Adolescents With Autism Spectrum Disorder Without Intellectual Disability: A Systematic Review.Journal of attention disorders · 2023Pooled it
- How 'core' are motor timing difficulties in ADHD? A latent class comparison of pure and comorbid ADHD classes.European child & adolescent psychiatry · 2016Trial
- Attention and learning strategies reveal distinct dimensions of psychiatric diseases.Research square · 2026Article
- Intraindividual Variability in Attention-Deficit/Hyperactivity Disorder: An Ex-Gaussian Approach.Child psychiatry and human development · 2026Article
- Template-based attentional guidance and generic procedural learning in contextual guided visual search: Evidence from reduced response time variability.Journal of vision · 2025Article
- Atypical Tactile Perception in Early Childhood Autism.Journal of autism and developmental disorders · 2023Article
- Reduced inferior fronto-insular-thalamic activation during failed inhibition in young adults with combined ASD and ADHD compared to typically developing and pure disorder groups.Translational psychiatry · 2023Article
- Visual search in neurodevelopmental disorders: evidence towards a continuum of impairment.European child & adolescent psychiatry · 2022Article
- Variability of Coordination in Typically Developing Children Versus Children with Autism Spectrum Disorder with and without Rhythmic Signal.Sensors (Basel, Switzerland) · 2020Article
- Significance of Beta-Band Oscillations in Autism Spectrum Disorders During Motor Response Inhibition Tasks: A MEG Study.Brain topography · 2020Article
- Decreased amplitude and reliability of odor-evoked responses in two mouse models of autism.Journal of neurophysiology · 2020Article
- Categorical and Dimensional Approaches to Examining the Joint Effect of Autism and Schizotypal Personality Disorder on Sustained Attention.Frontiers in psychiatry · 2020Article
- Implicit Measures of Receptive Vocabulary Knowledge in Individuals With Level 3 Autism.Cognitive and behavioral neurology : official journal of the Society for Behavioral and Cognitive Neurology · 2019Article
- Ex-Gaussian, Frequency and Reward Analyses Reveal Specificity of Reaction Time Fluctuations to ADHD and Not Autism Traits.Journal of abnormal child psychology · 2019Article
- Neuromotor and cognitive responses of adults with autism spectrum disorder compared to neurotypical adults.Experimental brain research · 2018Article
- Comorbid symptoms of inattention, autism, and executive cognition in youth with putative genetic risk.Journal of child psychology and psychiatry, and allied disciplines · 2018Article
- Depletion of Stercobilin in Fecal Matter from a Mouse Model of Autism Spectrum Disorders.Metabolomics : Official journal of the Metabolomic Society · 2017Article
- Broad Cognitive Profile in Children and Adolescents with HF-ASD and in Their Siblings: Widespread Underperformance and its Clinical and Adaptive Correlates.Journal of autism and developmental disorders · 2017Article
- Reproducibility of frequency-dependent low frequency fluctuations in reaction time over time and across tasks.PloS one · 2017Article
- Patterns of motor activity in spontaneously hypertensive rats compared to Wistar Kyoto rats.Behavioral and brain functions : BBF · 2016Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
Abstract
Despite the common co-occurrence of symptoms of attention deficit hyperactivity disorder (ADHD) in individuals with autism spectrum disorders (ASD), the underlying mechanisms are under-explored. A potential candidate for investigation is response time intra-subject variability (RT-ISV), a hypothesized marker of attentional lapses. Direct comparisons of RT-ISV in ASD versus ADHD are limited and contradictory. We aimed to examine whether distinct fluctuations in RT-ISV characterize children with ASD and with ADHD relative to typically developing children (TDC). We applied both a priori-based and data-driven strategies to RT performance of 46 children with ASD, 46 with ADHD, and 36 TDC (aged 7-11.9 years). Specifically, we contrasted groups relative to the amplitude of four preselected frequency bands as well as to 400 frequency bins from 0.006 to 0.345 Hz. In secondary analyses, we divided the ASD group into children with and without substantial ADHD symptoms (ASD(+) and ASD(-), respectively). Regardless of the strategy employed, RT-ISV fluctuations at frequencies between 0.20 and 0.345 Hz distinguished children with ADHD, but not children with ASD, from TDC. Children with ASD(+) and those with ADHD shared elevated amplitudes of RT-ISV fluctuations in frequencies between 0.18 and 0.345 Hz relative to TDC. In contrast, the ASD(-) subgroup did not differ from TDC in RT-ISV frequency fluctuations. RT-ISV fluctuations in frequencies 0.18-0.345 Hz (i.e., periods between 3 and 5 s) are associated with ADHD symptoms regardless of categorical diagnosis and may represent a biomarker. These results suggest that children with ADHD and those with ASD(+) share common underlying pathophysiological mechanisms of RT-ISV.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.