ArticleWorld journal of surgery2013
The prognostic relevance of psammoma bodies and ultrasonographic intratumoral calcifications in papillary thyroid carcinoma.
Article in World journal of surgery, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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22 citing papers in PubMed, 47 citations in OpenAlex.
- The impact of psammoma bodies on long-term prognosis in papillary thyroid carcinoma.Endocrine · 2026Article
- Clinical and morphological predictors of metastasis in papillary thyroid microcarcinoma.Frontiers in endocrinology · 2025Article
- Multifactorial risk stratification for central lymph node metastasis in papillary thyroid carcinoma: a predictive model integrating clinical and tumor characteristics.Frontiers in oncology · 2025Article
- Predicting central lymph node metastasis in papillary thyroid cancer: A nomogram based on clinical, ultrasound and contrast‑enhanced computed tomography characteristics.Oncology letters · 2024Article
- Stable thyroid cancer in a patient with thoracic aortic aneurysm and MYH11 variation.Endocrinology, diabetes & metabolism case reports · 2024Article
- Radiomics Features of Different Sizes of Medullary Thyroid Carcinoma (MTC) and Papillary Thyroid Carcinoma (PTC) Tumors: A Comparative Study.Clinical Medicine Insights. Oncology · 2022Article
- Microcalcifications without a thyroid nodule as the sole sign of papillary thyroid carcinoma.Endocrinology, diabetes & metabolism case reports · 2021Article
- Thyroid Parenchyma Microcalcifications on Ultrasound for Predicting Lymph Node Metastasis in Papillary Thyroid Carcinoma: A Prospective Multicenter Study in China.Frontiers in oncology · 2021Article
- Papillary thyroid carcinoma: an ultrasound-based nomogram improves the prediction of lymph node metastases in the central compartment.European radiology · 2020Article
- Clinicopathological Features as Prognostic Predictors of Poor Outcome in Papillary Thyroid Carcinoma.Cancers · 2020Article
- The comparison of accuracy of ultrasonographic features versus ultrasound-guided fine-needle aspiration cytology in diagnosis of malignant thyroid nodules.Journal of ultrasound · 2019Article
- Incidence and significance of psammoma bodies in Xp11.2 translocation renal cell carcinoma and papillary renal cell carcinoma.Oncology letters · 2019Article
- OPNa Overexpression Is Associated with Matrix Calcification in Thyroid Cancer Cell Lines.International journal of molecular sciences · 2018Article
- Calcification Patterns in Papillary Thyroid Carcinoma are Associated with Changes in Thyroid Hormones and Coronary Artery Calcification.Journal of clinical medicine · 2018Article
- Distribution patterns of microcalcifications in suspected thyroid carcinoma: a classification method helpful for diagnosis.European radiology · 2018Article
- Ultrasonographic Assessment of Differential Diagnosis Between Degenerating Cystic Thyroid Nodules and Papillary Thyroid Microcarcinomas.World journal of surgery · 2017Article
- Hypermetabolic Calcified Lymph Nodes on 18Fludeoxyglucose-Positron Emission Tomography/Computed Tomography in a Case of Treated Ovarian Cancer Recurrence: Residual Disease or Benign Formation?Molecular imaging and radionuclide therapy · 2016Article
- BRAF and epithelial-mesenchymal transition in papillary thyroid carcinoma - challenging the roles of Snail and E-Cadherin?American journal of translational research · 2016Article
- The Clinical Relevance of Psammoma Body and Hashimoto Thyroiditis in Papillary Thyroid Carcinoma: A Large Case-control Study.Medicine · 2015Article
- Total surface area is useful for differentiating between aggressive and favorable multifocal papillary thyroid carcinomas.Yonsei medical journal · 2015Article
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6 authors at 4 institutions in 1 country.
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Abstract
backgroundAlthough psammoma bodies (PB) are found in up to 50 % of papillary thyroid carcinomas (PTC), their clinicopathological significance remains uncertain. The aim of the present study was to determine the clinicopathological significance of PB and the correlation between PB and ultrasonographic intratumoral calcification in PTC.
methodsThe clinicopathological parameters, ultrasonographic calcifications, and the presence of PB were evaluated in 258 surgically resected conventional PTC.
resultsPsammoma bodies were found in 141 of 258 PTC (54.7 %). The presence of PB was significantly correlated with tumor multifocality, extrathyroidal extension, and lymph node metastasis (P = 0.009, P = 0.004, and P < 0.001, respectively), but not with the BRAF(V600E) mutation. Higher incidences of both intratumoral and extratumoral PB were found in overt PTC (>1 cm) than in papillary microcarcinomas (≤1 cm) (P < 0.001 and P = 0.015, respectively). Extratumoral PB were only identified in 48.9 % of 141 PTC with PB, and PTC with extratumoral PB showed higher incidences of tumor multifocality, extrathyroidal extension, and nodal metastasis compared to PTC with intratumoral PB (P = 0.014, P = 0.005 and P = 0.001, respectively). Ultrasonographic intratumoral calcification corresponded to clusters of intratumoral PB (P < 0.001) and was associated with nodal metastasis (P = 0.026).
conclusionsThe findings of the present study suggest that the presence of PB may be a useful prognostic indicator of aggressive PTC behaviors. In addition, confirmation of ultrasonographic intratumoral calcification would be a useful decision-making criterion when determining the need for preoperative or intraoperative surveillance of nodal metastasis.
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