ReviewCurrent cardiology reports2013
Risk of cardiovascular events with hormonal contraception: insights from the Danish cohort study.
Review in Current cardiology reports, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
8 citing papers in PubMed, 2 syntheses or guidelines pooled it, 20 citations in OpenAlex.
- Pooled it
- Association between duration of oral contraceptive use and risk of hypertension: A meta-analysis.Journal of clinical hypertension (Greenwich, Conn.) · 2017Pooled it
- Pregnancy in Women Receiving Maintenance Dialysis.Kidney medicine · 2025Review
- Oral contraceptives in adolescents: a retrospective population-based study on blood pressure and metabolic dysregulation.European journal of clinical pharmacology · 2024Article
- Biological Assessment of the NO-Dependent Endothelial Function.Molecules (Basel, Switzerland) · 2022Review
- Arterial Stiffness and Hemodynamics in Young Women: The Effects of Oral Contraceptive Intake and Physical Habits.International journal of environmental research and public health · 2021Article
- Comprehensive review of cardiovascular toxicity of drugs and related agents.Medicinal research reviews · 2018Review
- Vascular Disease in Young Indians (20-40 years): Role of Ischemic Heart Disease.Journal of clinical and diagnostic research : JCDR · 2016Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Hormonal contraception in the form of combined oral contraceptive pills is the most widely used reversible form of contraception in the US. Oral contraceptive (OC) pills have long been associated with risk of venous thromboembolism (VT) and arterial thrombosis (AT). There are more recent publications on risk of venous thromboembolism than arterial thrombosis. Many of the studies on AT have been contradictory in terms of results. The Danish cohort study is the largest study to date on the risk of AT in users of oral contraceptive pills. The study suggests that a lower estrogen dose may be better for preventing myocardial infarction and possibly thrombotic stroke but there is no significant difference according to progestin type for risk of thrombotic stroke or myocardial infarction. It challenges results of previous studies that show incremental risk of arterial thrombosis with smoking. The absolute and relative risks of arterial thrombosis in Danish women who used hormonal contraception were shown to be low. VT is more common than AT in women of reproductive age but AT is associated with a higher risk of mortality and disability. The decision to use hormonal contraceptives and the choice of formulation should be individualized based on patient's age and known risk factors for both VT and AT.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.