Evidence map›Paper›PMID 23715784›Full record

ReviewPediatric nephrology (Berlin, Germany)2014

Rational use of antihypertensive medications in children.

Michael A Ferguson, Joseph T Flynn

Abstract readReview
PubMed Publisher
In one paragraph

Review in Pediatric nephrology (Berlin, Germany), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Guideline
  2. Pharmacological Treatment of Arterial Hypertension in Children and Adolescents in Lithuania.International journal of environmental research and public health · 2022
    Article
  3. Brazilian Guidelines of Hypertension - 2020.Arquivos brasileiros de cardiologia · 2021
    Article
  4. Pediatric Obesity, Hypertension, Lipids.Current treatment options in pediatrics · 2020
    Article
  5. Article
  6. Article
  7. Evaluation and treatment of hypertensive crises in children.Integrated blood pressure control · 2016
    Review
  8. Review
  9. Review
  10. Review
  11. Participation of hypertension patients in early-phase clinical trials.Journal of clinical hypertension (Greenwich, Conn.) · 2014
    Article
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Michael A FergusonDivision of Nephrology, Boston Children's Hospital, Department of Pediatrics Harvard Medical School, Boston Children's Hospital, 300 Longwood Avenue, Boston, MA, 02115, USA, michael.ferguson@childrens.harvard.edu.
Joseph T Flynn

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hypertension has traditionally been regarded as an uncommon diagnosis in childhood and adolescence; however, there is compelling evidence to suggest that its prevalence is on the rise, particularly in those with obesity. As a result, pediatricians increasingly are asked to evaluate and manage patients with elevated blood pressure. An increased emphasis on conducting drug trials in children over the last 15 years has yielded important advances with respect to evidence-based data regarding the efficacy and safety of antihypertensive medications in children and adolescents. Unfortunately, data to definitively guide selection of initial agents is lacking. This article will present guidelines for the appropriate use of antihypertensive medications in the pediatric population, including the rational approach to selecting an appropriate medication with respect to pathophysiology, putative benefit, and likelihood for side effects.

Indexed as

AdolescentAntihypertensive AgentsChildHumansHypertensionAntihypertensive Agents

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.