Evidence map›Paper›PMID 23715580›Full record

GuidelineJournal of clinical oncology : official journal of the American Society of Clinical Oncology2013

Fertility preservation for patients with cancer: American Society of Clinical Oncology clinical practice guideline update.

Alison W Loren, Pamela B Mangu, Lindsay Nohr Beck, Lawrence Brennan, Anthony J Magdalinski, Ann H Partridge, Gwendolyn Quinn, W Hamish Wallace, Kutluk Oktay, American Society of Clinical Oncology

3 registry-linked trialsOpen access · bronzeAbstract readPractice GuidelineSystematic Review
In one paragraph

Guideline in Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 627 papers, 11 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
627citing papers in PubMed, 11 pooled it
158.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05299710 recruitingnot on this mapstarted 2018, after this paper: background citation

Ovarian Tissue Freezing for Fertility Preservation in Pre-Pubertal Children Facing a Fertility Threatening Medical Diagnosis or Treatment Regimen

Typeobservational_patient_registrySponsorErin RowellRan2018 to 2035Enrolled250ConditionsCancersArmsLaparoscopic surgery
NCT05309746 recruitingnot on this mapstarted 2017, after this paper: background citation

Ovarian Tissue Cryopreservation for Fertility Preservation in Post-Pubertal Children Facing a Fertility Threatening Diagnosis or Treatment Regimen

Typeobservational_patient_registrySponsorErin RowellRan2017 to 2035Enrolled250ConditionsPediatric CancerArmsLaparoscopic surgery
NCT07126561 phase2not yet recruitingnot on this mapstarted 2026, after this paper: background citation

Phase II Open Label Trial of Trastuzumab Deruxtecan (Enhertu, DS-8210) in HER2 Positive Newly Diagnosed Metastatic Esophageal, Gastric, GEJ Cancer Patients With an ECOG Performance Status of 2

TypeinterventionalSponsorUniversity of ChicagoRan2026 to 2028Enrolled43ConditionsHER2 Positive Newly Diagnosed Metastatic Esophageal, Gastric, GEJ Cancer Patients With an ECOG Performance Status of 2ArmsTrastuzumab Deruxtecan
3 · Its place in the literature

Who cites it

627 citing papers in PubMed, 11 syntheses or guidelines pooled it, 1,601 citations in OpenAlex.

  1. Pooled it
  2. Cancer and fertility management: FIGO best practice advice.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2025
    Guideline
  3. Guideline
  4. Pooled it
  5. Guideline
  6. Pooled it
  7. Pooled it
  8. Pooled it
  9. Guideline
  10. Pooled it
  11. The Educational Program for Healthcare Providers Regarding Fertility Preservation for Cancer Patients: a Systematic Review.Journal of cancer education : the official journal of the American Association for Cancer Education · 2021
    Pooled it
  12. Trial
  13. Review
  14. Initial development and usability testing of a digital fertility preservation navigator for newly diagnosed young adult cancer survivors.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Article
  15. Article
  16. Article
  17. Article
  18. Review
  19. Article
  20. Article

567 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Alison W LorenInstitute for Fertility Preservation, New York Medical College, Rye, NY, USA.
Pamela B Mangu
Lindsay Nohr Beck
Lawrence Brennan
Anthony J Magdalinski
Ann H Partridge
Gwendolyn Quinn
W Hamish Wallace
Kutluk Oktay
American Society of Clinical Oncology
American Society of Clinical Oncology · US

Funding

Characterization & Prevention of Chemotherapy-Induced Damage to Ovarian ReserveR01HD053112 · NICHD · YALE UNIVERSITY · PI KUTLUK H OKTAY · 2007 to 2026
$7.6M
NICHD NIH HHS R01 HD053112
6 · The paper itself

Abstract

purposeTo update guidance for health care providers about fertility preservation for adults and children with cancer.

methodsA systematic review of the literature published from March 2006 through January 2013 was completed using MEDLINE and the Cochrane Collaboration Library. An Update Panel reviewed the evidence and updated the recommendation language.

resultsThere were 222 new publications that met inclusion criteria. A majority were observational studies, cohort studies, and case series or reports, with few randomized clinical trials. After review of the new evidence, the Update Panel concluded that no major, substantive revisions to the 2006 American Society of Clinical Oncology recommendations were warranted, but clarifications were added. RECOMMENDATIONS: As part of education and informed consent before cancer therapy, health care providers (including medical oncologists, radiation oncologists, gynecologic oncologists, urologists, hematologists, pediatric oncologists, and surgeons) should address the possibility of infertility with patients treated during their reproductive years (or with parents or guardians of children) and be prepared to discuss fertility preservation options and/or to refer all potential patients to appropriate reproductive specialists. Although patients may be focused initially on their cancer diagnosis, the Update Panel encourages providers to advise patients regarding potential threats to fertility as early as possible in the treatment process so as to allow for the widest array of options for fertility preservation. The discussion should be documented. Sperm and embryo cryopreservation as well as oocyte cryopreservation are considered standard practice and are widely available. Other fertility preservation methods should be considered investigational and should be performed by providers with the necessary expertise.

Indexed as

CryopreservationAdolescentAdultChildCommunicationDecision MakingEmbryo, MammalianEvidence-Based MedicineFemaleFertilityHealthcare DisparitiesHealth Services AccessibilityHumansInfertilityInfertility, FemaleInfertility, Male

Identifiers

PMID23715580
PMCPMC5321083
OpenAlexW2142075003

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.