ArticleMolecular bioSystems2013
Multivalency amplifies the selection and affinity of bradykinin-derived peptides for lipid nanovesicles.
Article in Molecular bioSystems, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
16 citing papers in PubMed, 36 citations in OpenAlex.
- [Research progress of peptide recognition-guided strategies for exosome isolation and enrichment].Se pu = Chinese journal of chromatography · 2025Review
- Affinity-Based Isolation and One-Pot Analysis of Extracellular Vesicles from Biofluids Using Phase Separated Zwitterionic Coacervates.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Viral Membrane-Targeting Amphipathic Helical Peptide-Based Fluorogenic Probes for the Analysis of Infectious Titers of Enveloped Viruses.Analytical chemistry · 2025Article
- Engineered extracellular vesicles for tissue repair and regeneration.Burns & trauma · 2024Review
- Proof of concept of using a membrane-sensing peptide for sEVs affinity-based isolation.Frontiers in bioengineering and biotechnology · 2023Article
- Genetically Engineered Extracellular Vesicles Harboring Transmembrane Scaffolds Exhibit Differences in Their Size, Expression Levels of Specific Surface Markers and Cell-Uptake.Pharmaceutics · 2022Article
- Multivalent γ-PGA-Exendin-4 Conjugates to Target Pancreatic β-Cells.Chembiochem : a European journal of chemical biology · 2022Article
- Summary of Prof. Yin's CSEMV-EVCNA award lecture 2021.Extracellular vesicles and circulating nucleic acids · 2022Article
- Recent Progress of Exosome Isolation and Peptide Recognition-Guided Strategies for Exosome Research.Frontiers in chemistry · 2022Review
- Amphipathic helical peptide-based fluorogenic probes for a marker-free analysis of exosomes based on membrane-curvature sensing.RSC advances · 2020Article
- Membrane-binding peptides for extracellular vesicles on-chip analysis.Journal of extracellular vesicles · 2020Article
- Functional peptides for cartilage repair and regeneration.American journal of translational research · 2018Article
- Drugging Membrane Protein Interactions.Annual review of biomedical engineering · 2016Review
- Trigonal scaffolds for multivalent targeting of melanocortin receptors.Organic & biomolecular chemistry · 2015Article
- Exosomes and microvesicles: identification and targeting by particle size and lipid chemical probes.Chembiochem : a European journal of chemical biology · 2014Review
- Solution phase conformation and proteolytic stability of amide-linked neuraminic acid analogues.Biopolymers · 2013Article
Corrections and comments
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Authors and funding
9 authors at 3 institutions in 1 country.
Funding
Abstract
The trimer of a bradykinin derivative displayed a more than five-fold increase in binding affinity for phosphatidylserine-enriched nanovesicles as compared to its monomeric precursor. The nanovesicle selection is directly correlated with multivalency, which amplifies the electrostatic attraction. This strategy may lead to the development of novel molecular probes for detecting highly curved membrane bilayers.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.