ArticleJournal of acquired immune deficiency syndromes (1999)2013
The potential impact of expanding antiretroviral therapy and combination prevention in Vietnam: towards elimination of HIV transmission.
Article in Journal of acquired immune deficiency syndromes (1999), 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 38 papers, 7 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Prevalence, Socio-demographic Correlates of Substance Use Disorders Among HIV-infected Adults in Cameroon, and Their Influence on Adherence to Antiretroviral Therapy and Immunological Feature: Study Protocol for a Retrospective Cohort Study
HIV Awal (Early) Testing & Treatment Indonesia Project Implementing 'Test and Treat' Strategies for HIV Treatment and Prevention in Key Populations in Indonesia: a Prospective Implementation Research Study (Phase 1 - Observational Phase)
Who cites it
38 citing papers in PubMed, 7 syntheses or guidelines pooled it, 69 citations in OpenAlex.
- Pooled it
- Non-Adherence to Anti-Retroviral Therapy Among Adult People Living with HIV in Ethiopia: Systematic Review and Meta-Analysis.AIDS and behavior · 2024Pooled it
- Prevalence and shared risk factors of HIV in three key populations in Vietnam: A systematic review and meta-analysis.Epidemiology and infection · 2023Pooled it
- The costs of scaling up HIV and syphilis testing in low- and middle-income countries: a systematic review.Health policy and planning · 2021Pooled it
- Dynamic Transmission Economic Evaluation of Infectious Disease Interventions in Low- and Middle-Income Countries: A Systematic Literature Review.Health economics · 2016Pooled it
- Pooled it
- Towards universal voluntary HIV testing and counselling: a systematic review and meta-analysis of community-based approaches.PLoS medicine · 2013Pooled it
- Scaling Up HIV Self-Testing and Linkage to Care Among Women Who Exchange Sex and/or Use Drugs in Kazakhstan.AIDS education and prevention : official publication of the International Society for AIDS Education · 2024Article
- Cost-effectiveness of implementing HIV and HIV/syphilis dual testing among key populations in Viet Nam: a modelling analysis.BMJ open · 2022Article
- Factors affecting optimal adherence to antiretroviral therapy and viral suppression amongst HIV-infected prisoners in South Ethiopia: a comparative cross-sectional study.AIDS research and therapy · 2022Article
- Depression, antiretroviral therapy initiation, and HIV viral suppression among people who inject drugs in Vietnam.Journal of affective disorders · 2021Article
- Spatial distribution and characteristics of HIV clusters in Ethiopia.Tropical medicine & international health : TM & IH · 2020Article
- Patient satisfaction with HIV services in Vietnam: Status, service models and association with treatment outcome.PloS one · 2019Article
- Developing a dynamic HIV transmission model for 6 U.S. cities: An evidence synthesis.PloS one · 2019Article
- The Dark Side of Female HIV Patient Care: Sexual and Reproductive Health Risks in Pre- and Post-Clinical Treatments.Journal of clinical medicine · 2018Article
- A prospective "test-and-treat" demonstration project among people who inject drugs in Vietnam.Journal of the International AIDS Society · 2018Article
- Estimating retention in HIV care accounting for patient transfers: A national laboratory cohort study in South Africa.PLoS medicine · 2018Article
- Prevalence of Opportunistic Intestinal Parasites and Associated Factors among HIV Patients while Receiving ART at Arba Minch Hospital in Southern Ethiopia: A Cross-sectional Study.Ethiopian journal of health sciences · 2018Article
- High HIV Prevalence and Risk Among Male Clients of Female Sex Workers in Hanoi and Ho Chi Minh City, Vietnam.AIDS and behavior · 2017Article
- Exchange Sex and HIV Infection Among Men Who Have Sex with Men: 20 US Cities, 2011.AIDS and behavior · 2017Article
Corrections and comments
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Authors and funding
11 authors at 5 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundFew studies have assessed the effects of antiretroviral therapy (ART) to prevent HIV transmission in Asian HIV epidemics. Vietnam has a concentrated HIV epidemic with the highest prevalence among people who inject drugs. We investigated the impact of expanded HIV testing and counseling (HTC) and early ART, combined with other prevention interventions on HIV transmission.
methodsA deterministic mathematical model was developed using HIV prevalence trends in Can Tho province, Vietnam. Scenarios included offering periodic HTC and immediate ART with and without targeting subpopulations and examining combined strategies with methadone maintenance therapy and condom use.
resultsFrom 2011 to 2050, maintaining current interventions will incur an estimated 18,115 new HIV infections and will cost US $22.1 million (reference scenario). Annual HTC and immediate treatment, if offered to all adults, will reduce new HIV infections by 14,513 (80%) and will cost US $76.9 million. Annual HTC and immediate treatment offered only to people who inject drugs will reduce new infections by 13,578 (75%) and will cost only US $23.6 million. Annual HTC and immediate treatment for key populations, combined with scale-up of methadone maintenance therapy and condom use, will reduce new infections by 14,723 (81%) with similar costs (US $22.7 million). This combination prevention scenario will reduce the incidence to less than 1 per 100,000 in 14 years and will result in a relative cost saving after 19 years.
conclusionsTargeted periodic HTC and immediate ART combined with other interventions is cost-effective and could lead to potential elimination of HIV in Can Tho.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.